Maneepan Yawitta, Watcharawipha Anirut, Chitapanarux Imjai, Wanwilairat Somsak, Nobnop Wannapha
Medical Physics Program, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
The Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
J Appl Clin Med Phys. 2025 Apr;26(4):e14601. doi: 10.1002/acm2.14601. Epub 2024 Dec 3.
PreciseART, an adaptive radiation therapy (ART) software for helical tomotherapy (HT), was integrated into the Precision treatment planning system (Accuray, Inc., Sunnyvale, CA). It supports automatic monitoring of dose variations to both the target and organs at risk (OARs) throughout the treatment course. This study aims to verify the accuracy of PreciseART's automatic dose recalculation and assess the effectiveness of its notification function.
The Radixact X9's kVCT image-guided system (ClearRT) was used to acquire daily images for dose recalculations. We assessed the accuracy of PreciseART's automatic dose recalculation by comparing it with the treatment planning system (TPS) recalculation for the PTV70, spinal cord, and bilateral parotid glands. We also evaluated the efficacy of its notification function by comparing each dose metric for each notification color to TPS recalculation, assessing its role as a trigger tool.
In the phantom study, dosimetric analysis indicated no statistically significant differences between TPS and PreciseART recalculations (p > 0.05), with dose variations under 1.5%. Similarly, in the patient study (n = 10), no significant dosimetric discrepancies were found (p > 0.05), with a maximum variation of 2.3%. The notification system performed effectively, providing accurate notifications in accordance with predefined dose criteria.
PreciseART's daily dose recalculation demonstrated good agreement with TPS recalculation, and its notification function is effective for identifying dose threshold compliance, supporting its use in clinical ART.
PreciseART是一种用于螺旋断层放疗（HT）的自适应放疗（ART）软件，已集成到Precision治疗计划系统（Accuray公司，加利福尼亚州桑尼维尔）中。它支持在整个治疗过程中自动监测靶区和危及器官（OARs）的剂量变化。本研究旨在验证PreciseART自动剂量重新计算的准确性，并评估其通知功能的有效性。
使用Radixact X9的kVCT图像引导系统（ClearRT）获取每日图像以进行剂量重新计算。我们通过将PreciseART的自动剂量重新计算与治疗计划系统（TPS）对计划靶体积70（PTV70）、脊髓和双侧腮腺的重新计算进行比较，评估了PreciseART自动剂量重新计算的准确性。我们还通过将每个通知颜色的每个剂量指标与TPS重新计算进行比较，评估了其通知功能的有效性，评估了其作为触发工具的作用。
在模体研究中，剂量学分析表明TPS和PreciseART重新计算之间无统计学显著差异（p>0.05），剂量变化在1.5%以下。同样，在患者研究（n = 10）中，未发现显著的剂量学差异（p>0.05），最大变化为2.3%。通知系统运行有效，根据预定义的剂量标准提供准确的通知。
PreciseART的每日剂量重新计算与TPS重新计算显示出良好的一致性，其通知功能对于识别剂量阈值合规性有效，支持其在临床ART中的应用。
