Edalati Shaun, Ratna Sujay, Agarwal Parul, Harsinay Ariel, Rosenberg Joshua D, Gray Mingyang L
Department of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, 10029, United States.
Department of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY, 10029, United States.
Am J Otolaryngol. 2025 Jan-Feb;46(1):104547. doi: 10.1016/j.amjoto.2024.104547. Epub 2024 Dec 2.
Limited research exists on mental health disorders (MHDs) in Bell's palsy patients. This study investigates risk factors associated with the development of MHDs in these patients.
MarketScan commercial and Medicare outpatient and prescription drug claims data were utilized to conduct this study on adults with Bell's palsy. Patients were identified using International Classification of Diseases, Ninth or Tenth Revision, Clinical Modification diagnosis codes from 2014 to 2020 data. A one-year washout period was applied where patients did not have any diagnosis of MHD before Bell's palsy diagnosis. Patients were included if they were continuously enrolled for at least two years. The primary outcome was new-onset of any MHDs within one year of diagnosis of Bell's palsy. Descriptive statistics and logistic regression model explored risk factors associated with the development of any MHDs.
Out of 37,166 Bell's palsy patients (mean age 49; 50.4 % female), 8.27 % experienced new-onset MHDs, with anxiety being the most prevalent (3.88 %). Female sex [Adjusted odds ratio (AOR) 1.40, 95 % CI 1.30-1.51, p < 0.0001], increasing Charlson comorbidity index (AOR 1.11, 95 % CI 1.04-1.176, p = 0.001), and symptoms like headache (AOR 1.16, 95 % CI 1.34-1.81, p < 0.0001) and facial pain (AOR 1.71, 95 % CI 1.15-2.52, p = 0.007) were associated with increased odds of new-onset of MHDs.
Bell's palsy patients can develop MHDs within first year of diagnosis, although the incidence of MHDs in this cohort is lower than that of the general population. Several factors are associated with the development of MHDs. These findings underscore the significance of addressing mental health in Bell's palsy patients, offering valuable considerations for clinical care and future research.
关于贝尔面瘫患者心理健康障碍(MHDs)的研究有限。本研究调查这些患者发生MHDs的相关危险因素。
利用MarketScan商业保险和医疗保险门诊及处方药索赔数据,对成年贝尔面瘫患者进行本研究。通过2014年至2020年数据中的国际疾病分类第九版或第十版临床修订诊断代码识别患者。采用一年的洗脱期,即患者在贝尔面瘫诊断前未被诊断出患有任何MHDs。若患者连续登记至少两年则纳入研究。主要结局是贝尔面瘫诊断后一年内新发的任何MHDs。描述性统计和逻辑回归模型探讨了与任何MHDs发生相关的危险因素。
在37166例贝尔面瘫患者(平均年龄49岁;50.4%为女性)中,8.27%经历了新发MHDs,其中焦虑最为常见(3.88%)。女性[调整后的优势比(AOR)1.40,95%置信区间1.30 - 1.51,p < 0.0001]、查尔森合并症指数增加(AOR 1.11,95%置信区间1.04 - 1.176,p = 0.001)以及头痛(AOR 1.16,95%置信区间1.34 - 1.81,p < 0.0001)和面部疼痛(AOR 1.71,95%置信区间1.15 - 2.52,p = 0.007)等症状与新发MHDs的几率增加相关。
贝尔面瘫患者在诊断后的第一年内可能发生MHDs,尽管该队列中MHDs的发病率低于一般人群。有几个因素与MHDs的发生相关。这些发现强调了关注贝尔面瘫患者心理健康的重要性,为临床护理和未来研究提供了有价值的参考。