Dedhia Kavita, Maltenfort Mitchell, Briddell Jenna, Horn David, Li Carol, Pattisapu Prasanth, Preciado Diego, Pritchett Cedric V, Wine Todd, Forrest Christopher B
The Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Applied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.
Laryngoscope. 2025 May;135(5):1821-1829. doi: 10.1002/lary.31916. Epub 2024 Dec 5.
To evaluate temporal trends and identify patient characteristics associated with otitis media (OM) surgery.
A retrospective cohort study performed using electronic health record data from seven large pediatric medical networks from January 1, 2009, to December 31, 2022. Children <6 months old cohort entrance time and OM history were included and followed longitudinally.
The database included 1,448,390 children entering at age <6 months of which 5.3% underwent tympanostomy tube insertion (TTI). Inclusion criteria was met by 454,924 children. Age at first OM was 1.6 years (standard deviation [SD]: 1.1), with mean follow-up of 6.3 years (SD 3.7), and 249,818 (54.9%) were male. Among children with OM 64,950 (14.3%) underwent only TTI, and 13,188 (2.9%) had TTI with adenoidectomy (TTI-A). Over time, TTI only rates exhibited seasonal fluctuations with a drop in 2020, TTI-A rates were flat. The following patient characteristics greatly increased TTI: sensorineural hearing loss (adjusted hazard ratio, aHR 4.0, [95% confidence interval, CI] 3.9-4.1), chronic adenoiditis (aHR 3.4 [95% CI 3.0-3.5]), and cleft palate (aHR 1.9 [95% CI 1.8-2.0]). Children 4-8 years old (aHR >11.7 [95% CI 10.6-16.4]), history of chronic adenoiditis (aHR 6.4 [95% CI 5.4-7.7]), or sleep disorders (aHR 4.9 [95% CI 4.7-5.2]) greatly increased TTI-A odds.
Overall TTI rate was 5.3%, which increased to approximately 20% in children with OM. Aside from the COVID-19 pandemic, surgical rates have been stable. Though multiple characteristics increase the risk of TTI, sensorineural hearing loss for TTI only, and older age in the TTI-A subset carried the highest risk.
3 Laryngoscope, 135:1821-1829, 2025.
评估中耳炎(OM)手术的时间趋势并确定与之相关的患者特征。
一项回顾性队列研究,使用来自七个大型儿科医疗网络2009年1月1日至2022年12月31日的电子健康记录数据。纳入6个月以下队列进入时间且有OM病史的儿童并进行纵向随访。
数据库包括1448390名6个月以下进入队列的儿童,其中5.3%接受了鼓膜置管术(TTI)。454924名儿童符合纳入标准。首次发生OM的年龄为1.6岁(标准差[SD]:1.1),平均随访6.3年(SD 3.7),男性249818名(54.9%)。在患有OM的儿童中,64950名(14.3%)仅接受了TTI,13188名(2.9%)接受了TTI联合腺样体切除术(TTI-A)。随着时间的推移,仅TTI的发生率呈现季节性波动,在2020年有所下降,TTI-A的发生率则较为平稳。以下患者特征显著增加了TTI的风险:感音神经性听力损失(调整后风险比,aHR 4.0,[95%置信区间,CI] 3.9 - 4.1)、慢性腺样体炎(aHR 3.4 [95% CI 3.0 - 3.5])和腭裂(aHR 1.9 [95% CI 1.8 - 2.0])。4 - 8岁的儿童(aHR >11.7 [95% CI 10.6 - 16.4])、有慢性腺样体炎病史(aHR 6.4 [95% CI 5.4 - 7.7])或睡眠障碍(aHR 4.9 [95% CI 4.7 - 5.2])显著增加了TTI-A的几率。
总体TTI发生率为5.3%,在患有OM的儿童中增至约20%。除了新冠疫情期间,手术率一直保持稳定。尽管多种特征增加了TTI的风险,但仅TTI中的感音神经性听力损失以及TTI-A亚组中的年龄较大者风险最高。
3 喉镜,135:1821 - 1829,2025年