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中耳炎手术的时间趋势及相关患者特征

Temporal Trends in and Patient Characteristics Associated with Surgery for Otitis Media.

作者信息

Dedhia Kavita, Maltenfort Mitchell, Briddell Jenna, Horn David, Li Carol, Pattisapu Prasanth, Preciado Diego, Pritchett Cedric V, Wine Todd, Forrest Christopher B

机构信息

The Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.

Applied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.

出版信息

Laryngoscope. 2025 May;135(5):1821-1829. doi: 10.1002/lary.31916. Epub 2024 Dec 5.

Abstract

OBJECTIVES

To evaluate temporal trends and identify patient characteristics associated with otitis media (OM) surgery.

METHODS

A retrospective cohort study performed using electronic health record data from seven large pediatric medical networks from January 1, 2009, to December 31, 2022. Children <6 months old cohort entrance time and OM history were included and followed longitudinally.

RESULTS

The database included 1,448,390 children entering at age <6 months of which 5.3% underwent tympanostomy tube insertion (TTI). Inclusion criteria was met by 454,924 children. Age at first OM was 1.6 years (standard deviation [SD]: 1.1), with mean follow-up of 6.3 years (SD 3.7), and 249,818 (54.9%) were male. Among children with OM 64,950 (14.3%) underwent only TTI, and 13,188 (2.9%) had TTI with adenoidectomy (TTI-A). Over time, TTI only rates exhibited seasonal fluctuations with a drop in 2020, TTI-A rates were flat. The following patient characteristics greatly increased TTI: sensorineural hearing loss (adjusted hazard ratio, aHR 4.0, [95% confidence interval, CI] 3.9-4.1), chronic adenoiditis (aHR 3.4 [95% CI 3.0-3.5]), and cleft palate (aHR 1.9 [95% CI 1.8-2.0]). Children 4-8 years old (aHR >11.7 [95% CI 10.6-16.4]), history of chronic adenoiditis (aHR 6.4 [95% CI 5.4-7.7]), or sleep disorders (aHR 4.9 [95% CI 4.7-5.2]) greatly increased TTI-A odds.

CONCLUSIONS

Overall TTI rate was 5.3%, which increased to approximately 20% in children with OM. Aside from the COVID-19 pandemic, surgical rates have been stable. Though multiple characteristics increase the risk of TTI, sensorineural hearing loss for TTI only, and older age in the TTI-A subset carried the highest risk.

LEVEL OF EVIDENCE

3 Laryngoscope, 135:1821-1829, 2025.

摘要

目的

评估中耳炎(OM)手术的时间趋势并确定与之相关的患者特征。

方法

一项回顾性队列研究,使用来自七个大型儿科医疗网络2009年1月1日至2022年12月31日的电子健康记录数据。纳入6个月以下队列进入时间且有OM病史的儿童并进行纵向随访。

结果

数据库包括1448390名6个月以下进入队列的儿童,其中5.3%接受了鼓膜置管术(TTI)。454924名儿童符合纳入标准。首次发生OM的年龄为1.6岁(标准差[SD]:1.1),平均随访6.3年(SD 3.7),男性249818名(54.9%)。在患有OM的儿童中,64950名(14.3%)仅接受了TTI,13188名(2.9%)接受了TTI联合腺样体切除术(TTI-A)。随着时间的推移,仅TTI的发生率呈现季节性波动,在2020年有所下降,TTI-A的发生率则较为平稳。以下患者特征显著增加了TTI的风险:感音神经性听力损失(调整后风险比,aHR 4.0,[95%置信区间,CI] 3.9 - 4.1)、慢性腺样体炎(aHR 3.4 [95% CI 3.0 - 3.5])和腭裂(aHR 1.9 [95% CI 1.8 - 2.0])。4 - 8岁的儿童(aHR >11.7 [95% CI 10.6 - 16.4])、有慢性腺样体炎病史(aHR 6.4 [95% CI 5.4 - 7.7])或睡眠障碍(aHR 4.9 [95% CI 4.7 - 5.2])显著增加了TTI-A的几率。

结论

总体TTI发生率为5.3%,在患有OM的儿童中增至约20%。除了新冠疫情期间,手术率一直保持稳定。尽管多种特征增加了TTI的风险,但仅TTI中的感音神经性听力损失以及TTI-A亚组中的年龄较大者风险最高。

证据级别

3 喉镜,135:1821 - 1829,2025年

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ee/11980967/308941140e16/LARY-135-1821-g003.jpg

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