Kay R, Lattanzi C
J Urol. 1985 Jan;133(1):99-101. doi: 10.1016/s0022-5347(17)48806-9.
Nephrogenic adenoma is a rare, benign lesion of the bladder, occurring as an epithelial response to infection or trauma. Characteristically, it presents as a papillary lesion resembling a low grade, low stage transitional cell carcinoma. Although usually occurring in adults, there have been 5 reports in children, in whom the adenoma occurred following either surgery or localized inflammation. We report on 2 additional children with nephrogenic adenoma, including one who presented with a bladder mass and total occlusion of the ipsilateral ureter, while in the other it was found incidentally during closure of a vesicovaginal fistula. Successful treatment consisted of transurethral resection and low dose suppressive antibiotics. Nephrogenic adenoma, while rare in children, appears to be a uroepithelial metaplastic response to trauma or inflammation and is treated best by conservative management.
肾源性腺瘤是一种罕见的膀胱良性病变，是上皮对感染或创伤的反应。其特征表现为乳头状病变，类似于低级别、低分期的移行细胞癌。虽然通常发生于成人，但已有5例儿童病例报道，这些儿童的腺瘤发生于手术或局部炎症之后。我们报告另外2例儿童肾源性腺瘤病例，其中1例表现为膀胱肿块并同侧输尿管完全梗阻，另1例在膀胱阴道瘘修补术中偶然发现。成功的治疗方法包括经尿道切除术和低剂量抑制性抗生素治疗。肾源性腺瘤在儿童中虽罕见，但似乎是尿路上皮对创伤或炎症的化生反应，最佳治疗方法是保守治疗。
