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卒中相关性肌少症:病理生理学与诊断工具

Stroke-Related Sarcopenia: Pathophysiology and Diagnostic Tools.

作者信息

Chon Jinmann, Soh Yunsoo, Shim Ga Yang

机构信息

Department of Physical and Rehabilitation Medicine, Kyung Hee University Hospital, Seoul, Korea.

出版信息

Brain Neurorehabil. 2024 Nov 27;17(3):e23. doi: 10.12786/bn.2024.17.e23. eCollection 2024 Nov.

DOI:10.12786/bn.2024.17.e23
PMID:39649713
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11621676/
Abstract

Sarcopenia is characterized by the progressive loss of muscle mass and strength and can be categorized as either primary or secondary. Patients who have experienced a stroke may develop sarcopenia, which can adversely impact their functional recovery. The pathophysiology of sarcopenia related to stroke involves nutritional deficiency, disuse atrophy, denervation, and metabolic disturbance. Various evaluation tools are available to diagnose this condition, assessing skeletal muscle mass, muscle strength, and physical function. However, due to the limitations of traditional sarcopenia diagnostic criteria in the context of stroke, there is pressing need to establish diagnostic standards that accurately reflect the disabilities experienced by patients with stroke.

摘要

肌肉减少症的特征是肌肉质量和力量逐渐丧失,可分为原发性或继发性。经历过中风的患者可能会出现肌肉减少症,这会对他们的功能恢复产生不利影响。与中风相关的肌肉减少症的病理生理学涉及营养缺乏、废用性萎缩、去神经支配和代谢紊乱。有多种评估工具可用于诊断这种情况,评估骨骼肌质量、肌肉力量和身体功能。然而,由于传统的肌肉减少症诊断标准在中风背景下存在局限性,迫切需要建立能够准确反映中风患者所经历残疾的诊断标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1485/11621676/28e180d1dfe2/bn-17-e23-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1485/11621676/28e180d1dfe2/bn-17-e23-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1485/11621676/28e180d1dfe2/bn-17-e23-g001.jpg

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J Back Musculoskelet Rehabil. 2024;37(5):1345-1354. doi: 10.3233/BMR-230423.
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Prevalence and risk factors of possible sarcopenia in patients with subacute stroke.亚急性脑卒中患者可能发生肌肉减少症的患病率和危险因素。
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中风后患者的肌肉减少症:患病率及相关因素。
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Effectiveness of Rehabilitation Exercise in Improving Physical Function of Stroke Patients: A Systematic Review.康复运动改善脑卒中患者身体功能的效果:系统评价。
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Aging after stroke: how to define post-stroke sarcopenia and what are its risk factors?中风后的衰老:如何定义中风后肌少症及其危险因素?
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