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东开普省医院中糖尿病相关下肢截肢患者的存活率。

Survival rate of diabetic-related lower extremity amputees in hospitals in the Eastern Cape.

作者信息

Mgibantaka Aviwe S, Musekiwa Alfred, Zunza Moleen

机构信息

Division of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa.

Department of Rehabilitation Medicine, Faculty of Medicine and Health Sciences, Walter Sisulu University, Mthatha, South Africa.

出版信息

Afr J Disabil. 2024 Nov 15;13:1503. doi: 10.4102/ajod.v13i0.1503. eCollection 2024.

Abstract

BACKGROUND

Diabetes mellitus (DM) is a global health concern that has greatly affected South Africa. The gap in the current management of DM has resulted in complications such as lower extremity amputations (LEAs) and death. Eastern Cape province reflects this struggle, with disparities in access to healthcare and poor health outcomes. Understanding survival rates and associated factors between the urban Livingstone Hospital and the rural Nelson Mandela Academic Hospital can improve health interventions and outcomes.

OBJECTIVES

This study compared the survival rate of patients in urban areas and those in rural areas.

METHOD

This retrospective cohort study was conducted in an urban and a rural hospital by reviewing existing medical records of diabetic patients who underwent an LEA between 2016 and 2019.

RESULTS

The retrospective cohort study examined 439 diabetic-related LEA cases. This study found that residing in rural areas significantly decreased the risk of mortality by 62% compared with living in the urban areas. Factors such as haemoglobin A1c (HbA1c) levels, nephropathy, cardiovascular disease, human immunodeficiency virus (HIV), other comorbidities and level of amputation significantly influenced survival probabilities.

CONCLUSION

Survival analysis indicated a significant difference in the 3-year survival probabilities of the two groups, favouring rural residency ( = 0.001). The biggest cause for concern between the two regions was uncontrolled blood glucose levels as this resulted in high mortality rates.

CONTRIBUTION

Insights from this study have shown that introducing podiatry and orthotics at primary healthcare (PHC) could improve foot care and reduce diabetic-related LEAs and mortality.

摘要

背景

糖尿病是一个全球性的健康问题,对南非产生了重大影响。目前糖尿病管理方面的差距已导致诸如下肢截肢和死亡等并发症。东开普省反映了这一困境,在医疗保健可及性方面存在差异且健康结果不佳。了解城市的利文斯通医院和农村的纳尔逊·曼德拉学术医院之间的生存率及相关因素,有助于改善健康干预措施和结果。

目的

本研究比较了城市地区和农村地区患者的生存率。

方法

这项回顾性队列研究在一家城市医院和一家农村医院开展,通过查阅2016年至2019年期间接受下肢截肢手术的糖尿病患者的现有病历进行。

结果

该回顾性队列研究检查了439例与糖尿病相关的下肢截肢病例。研究发现,与居住在城市地区相比,居住在农村地区可使死亡风险显著降低62%。糖化血红蛋白(HbA1c)水平、肾病、心血管疾病、人类免疫缺陷病毒(HIV)、其他合并症以及截肢水平等因素对生存概率有显著影响。

结论

生存分析表明两组的3年生存概率存在显著差异,农村居民更具优势(P = 0.001)。两个地区最令人担忧的问题是血糖水平控制不佳,因为这导致了高死亡率。

贡献

本研究的见解表明,在初级卫生保健(PHC)中引入足病学和矫形学可改善足部护理,降低与糖尿病相关的下肢截肢率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c274/11621866/2a9a4399658f/AJOD-13-1503-g001.jpg

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