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新陈代谢中的心智——关于糖尿病及其与强迫症、精神分裂症和双相情感障碍关联的综合文献综述

Mind in Metabolism - A Comprehensive Literature Review on Diabetes and its Connections to Obsessive Compulsive Disorder, Schizophrenia, and Bipolar Disorder.

作者信息

Cannon Anja, Jacoby Caitlon, Hughes Allyson S

机构信息

Department of Primary Care, Diabetes Institute, Institute to Advance Health Equity (ADVANCE), Ohio University Heritage College of Osteopathic Medicine, 102 W Green Dr, Athens, OH, 45701, USA.

出版信息

Curr Diab Rep. 2024 Dec 9;25(1):10. doi: 10.1007/s11892-024-01564-0.

Abstract

PURPOSE OF REVIEW

The co-occurrence of diabetes and mental illnesses such as bipolar disorder (BD), obsessive-compulsive disorder (OCD), and schizophrenia creates significant barriers for both people with diabetes (PWD) and their healthcare teams. This literature review provides an analysis of the relationship between diabetes and mental illnesses through exploring epidemiology, shared risk factors, and clinical implications. The aim is to enhance the understanding of these complex comorbidities to guide and improve future research and clinical practice.

RECENT FINDINGS

Recent research suggests a strong link between mental illness, metabolic syndrome, and diabetes. Studies show that BD has a robust relationship with metabolic disease and the antipsychotic medications used in treatment for many mental illnesses are strongly associated with weight gain and metabolic disease. However, there is limited research exploring the bidirectional relationship that diabetes has with BD, schizophrenia, and OCD. While research exists on the link between diabetes and mental conditions such as depression and anxiety, little research has examined schizophrenia, OCD and BD. The findings noted in this review suggest gaps in treatment options, healthcare services, and social support. While this paper provides a foundation for future progress, advancement in this field will require a collaborative effort from researchers, healthcare professionals, and community outreach programs to effectively close the gaps in care noted in these patient populations.

摘要

综述目的

糖尿病与双相情感障碍(BD)、强迫症(OCD)和精神分裂症等精神疾病并存,给糖尿病患者(PWD)及其医疗团队都带来了重大障碍。本文献综述通过探讨流行病学、共同风险因素和临床意义,分析糖尿病与精神疾病之间的关系。目的是增进对这些复杂共病的理解,以指导和改进未来的研究及临床实践。

最新发现

近期研究表明精神疾病、代谢综合征和糖尿病之间存在紧密联系。研究显示双相情感障碍与代谢疾病有密切关系,许多精神疾病治疗中使用的抗精神病药物与体重增加和代谢疾病密切相关。然而,探讨糖尿病与双相情感障碍、精神分裂症和强迫症之间双向关系的研究有限。虽然存在关于糖尿病与抑郁症和焦虑症等精神状况之间联系的研究,但很少有研究涉及精神分裂症、强迫症和双相情感障碍。本综述中指出的研究结果表明在治疗选择、医疗服务和社会支持方面存在差距。虽然本文为未来进展奠定了基础,但该领域的进步需要研究人员、医疗专业人员和社区外展项目共同努力,以有效填补这些患者群体中所发现的护理差距。

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