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全膝关节置换术后患者报告的结局与功能实时客观测量指标之间有何关联?一项使用每日步态指标的前瞻性研究。

How Do Patient-Reported Outcomes Correlate With Real-Time Objective Measures of Function After Total Knee Arthroplasty? A Prospective Study Using Daily Gait Metrics.

作者信息

Wu Kevin A, Kugelman David N, Goel Rahul K, Dilbone Eric S, Ryan Sean P, Wellman Samuel S, Bolognesi Michael P, Seyler Thorsten M

机构信息

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.

出版信息

J Arthroplasty. 2025 Jul;40(7):1711-1718. doi: 10.1016/j.arth.2024.12.007. Epub 2024 Dec 10.

Abstract

BACKGROUND

Patient-reported outcomes (PROs) are essential for evaluating patients undergoing total knee arthroplasty (TKA). While wearable technologies offer objective measures of physical function through Apple HealthKit, their relationship with PROs in TKA patients is not well understood. We investigated the association between commonly used PROs and objective measures of physical function in patients undergoing TKA.

METHODS

We conducted a prospective cohort study involving 152 patients undergoing unilateral TKA, assessing PROs (Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, and EuroQol Five-Dimensional Questionnaire) and objective HealthKit metrics (gait speed, step count, standing duration, steadiness, and estimated 6-minute walk test) before and at one, six, and 12 months after surgery. Pearson correlation coefficients were used to analyze the relationship between PROs and HealthKit metrics at each time point, adjusting for multiple comparisons.

RESULTS

Significant improvements were observed in PROs post-TKA. The Knee Injury and Osteoarthritis Outcome Score, Joint Replacement, scores improved from 52.1 ± 11.9 preoperatively to 82.5 ± 13.2 at 12 months postoperatively (P < 0.001), and EuroQol Five-Dimensional Questionnaire scores improved from 73.9 ± 17.8 to 85.7 ± 11.6 over the same period (P < 0.001). However, correlations between PROs and HealthKit metrics were consistently low (mean r = 0.2 to 0.3) and not significant after adjusting for multiple comparisons at various operative time points. Notably, correlations among HealthKit metrics themselves remained high, indicating that objective measures were internally consistent but not strongly related to PROs.

CONCLUSIONS

Despite their importance in patient-centered care, PROs may not fully reflect actual physical function. Clinicians should consider incorporating objective measures, such as those provided by HealthKit, into routine assessments to obtain a more comprehensive view of patient recovery post-TKA.

摘要

背景

患者报告结局(PROs)对于评估接受全膝关节置换术(TKA)的患者至关重要。虽然可穿戴技术通过苹果健康套件提供身体功能的客观测量指标,但其与TKA患者PROs之间的关系尚未得到充分理解。我们研究了TKA患者常用的PROs与身体功能客观测量指标之间的关联。

方法

我们进行了一项前瞻性队列研究,纳入152例接受单侧TKA的患者,在手术前以及术后1个月、6个月和12个月评估PROs(膝关节损伤和骨关节炎结局评分、关节置换和欧洲五维健康量表问卷)以及健康套件的客观指标(步态速度、步数、站立持续时间、稳定性和估计的6分钟步行试验)。使用Pearson相关系数分析每个时间点PROs与健康套件指标之间的关系,并对多重比较进行校正。

结果

TKA术后PROs有显著改善。膝关节损伤和骨关节炎结局评分、关节置换评分从术前的52.1±11.9提高到术后12个月的82.5±13.2(P<0.001),同期欧洲五维健康量表问卷评分从73.9±17.8提高到85.7±11.6(P<0.001)。然而,PROs与健康套件指标之间的相关性始终较低(平均r=0.2至0.3),在对不同手术时间点的多重比较进行校正后无统计学意义。值得注意的是,健康套件指标之间的相关性仍然很高,表明客观测量指标内部一致,但与PROs的相关性不强。

结论

尽管PROs在以患者为中心的护理中很重要,但它们可能无法完全反映实际身体功能。临床医生应考虑将客观测量指标,如健康套件提供的指标,纳入常规评估,以更全面地了解TKA术后患者的恢复情况。

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