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一种以吞咽困难为导向的牛肌腱胶原蛋白-木薯淀粉复合凝胶基质的新策略。

A novel strategy of dysphagia-oriented matrices bovine tendon collagen-cassava starch composite gels.

作者信息

Lin Yuhong, Wang Zhuo, Shi Chaoxue, Han Ling, Yu Qunli

机构信息

College of Food Science and Engineering, Gansu Agricultural University, Lanzhou 730070, China.

College of Food Science and Engineering, Gansu Agricultural University, Lanzhou 730070, China.

出版信息

Int J Biol Macromol. 2025 Feb;288:138691. doi: 10.1016/j.ijbiomac.2024.138691. Epub 2024 Dec 11.

Abstract

Dysphagia foods are designed for individuals with swallowing difficulties to consume safely. Texture-modified diets have become essential in dysphagia management. This study aimed to assess the safety and effectiveness of bovine tendon collagen (BTC) as a texture modifier to alter the starch gel network through a synergistic effect with cassava starch (CS), enhancing its application in dysphagia foods. The results indicated that BTC addition initially reduced gel water retention then increased, with a minimum observed at 2 % BTC. However, all gels demonstrated excellent WHC. The viscoelasticity, hardness, adhesion, gumminess, and thermal stability of composite gels improved with rising BTC concentrations. Secondary structure analysis revealed BTC altered the ordered structures of CS, with hydrogen bonds playing a key role. The microstructure showed that BTC disrupted and attached to the gel network, forming a more compact structure. Additionally, BTC inhibited CS digestion, increasing resistant starch content and decreasing rapidly digestible starch content. Furthermore, International Dysphagia Diet Standardization Initiative tests indicated that 2 % BTC gels could be categorized as level 4 (pureed or extremely thick), while gels with 4-6 % BTC could be classified as level 5 (minced and moist). These findings highlight the potential of BTC-CS composite gels for innovative dysphagia food development.

摘要

吞咽困难食物是为吞咽困难的个体设计的,以便他们能够安全食用。质地改良饮食在吞咽困难管理中已变得至关重要。本研究旨在评估牛肌腱胶原蛋白(BTC)作为一种质地改良剂,通过与木薯淀粉(CS)协同作用改变淀粉凝胶网络,增强其在吞咽困难食物中的应用的安全性和有效性。结果表明,添加BTC最初会降低凝胶保水性,随后增加,在2% BTC时观察到最小值。然而,所有凝胶均表现出优异的保水性。复合凝胶的粘弹性、硬度、粘附性、胶粘性和热稳定性随着BTC浓度的升高而提高。二级结构分析表明,BTC改变了CS的有序结构,氢键起关键作用。微观结构显示,BTC破坏并附着在凝胶网络上,形成更致密的结构。此外,BTC抑制CS消化,增加抗性淀粉含量,降低快速消化淀粉含量。此外,国际吞咽困难饮食标准化倡议测试表明,2% BTC凝胶可归类为4级(泥状或极稠),而4 - 6% BTC凝胶可归类为5级(切碎且湿润)。这些发现突出了BTC - CS复合凝胶在创新吞咽困难食物开发中的潜力。

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