Conroy Grace M, Marut Danielle M, Gomes Joao A, Street Sarah, Idoine Julie, Ahrens Christine
Department of Pharmacy, Cleveland Clinic, Cleveland, OH, USA.
Cereberovascular Center, Cleveland Clinic, Cleveland, OH, USA.
J Pharm Pract. 2025 Aug;38(4):390-396. doi: 10.1177/08971900241308624. Epub 2024 Dec 13.
Traditional Post-Intensive Care Recovery Clinics (PIRCs) often exclude neurocritical care patients. In 2020, a multidisciplinary team started Post Neuro Intensive Care Virtual Clinic (PREVAIL) that uses telemedicine to provide consultative care for patients with a primary neurologic injury who are at risk for post-intensive care syndrome. During clinic, critical care pharmacists perform medication reconciliations and provide drug therapy recommendations. The objective of this observational review is to describe the pharmacists' interventions and role in a novel PIRC. A retrospective, observational review was conducted for patients who were seen in PREVAIL from December 2020 to January 2022. The pharmacist completed a medication reconciliation and provided drug therapy recommendations. Amongst fifty-two PREVAIL patients, the most common neurologic diagnosis was intracerebral hemorrhage, seizures, and acute ischemic stroke. All patients were mechanically ventilated during their ICU stay, with a median ICU length of stay of 17 days [IQR 10-26]. After medication reconciliation, 93% of patients required adjustments to their medication list. After patient examination, 89% of patients required a drug therapy recommendation, with a median of three interventions per patient. Various medication classes were intervened on, most frequently antipsychotics, anti-seizure medications, antihypertensives, anticoagulants, neuromodulators, and antidepressants. This is the first study to evaluate pharmacist contributions at a consultative telemedicine PIRC that focuses on providing care for patients with a primary neurologic injury. PREVAIL pharmacists have a crucial role in the multidisciplinary team. Future research is required to determine the pharmacist's impact on clinical outcomes.
传统的重症监护后康复诊所(PIRCs)通常将神经重症监护患者排除在外。2020年,一个多学科团队启动了神经重症监护后虚拟诊所(PREVAIL),该诊所利用远程医疗为有重症监护后综合征风险的原发性神经损伤患者提供咨询护理。在诊所期间,重症监护药剂师进行用药核对并提供药物治疗建议。本观察性综述的目的是描述药剂师在新型PIRC中的干预措施和作用。对2020年12月至2022年1月在PREVAIL就诊的患者进行了回顾性观察性综述。药剂师完成了用药核对并提供了药物治疗建议。在52名PREVAIL患者中,最常见的神经诊断是脑出血、癫痫发作和急性缺血性中风。所有患者在重症监护病房(ICU)住院期间均接受机械通气,ICU中位住院时间为17天[四分位间距10 - 26天]。用药核对后,93%的患者需要调整用药清单。在对患者进行检查后,89%的患者需要药物治疗建议,每位患者平均有三次干预。对各类药物进行了干预,最常见的是抗精神病药、抗癫痫药、抗高血压药、抗凝药、神经调节剂和抗抑郁药。这是第一项评估药剂师在专注于为原发性神经损伤患者提供护理的咨询远程医疗PIRC中的贡献的研究。PREVAIL药剂师在多学科团队中发挥着关键作用。需要进一步的研究来确定药剂师对临床结果的影响。