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嗜铬细胞瘤诱发的心源性休克需体外膜肺氧合支持:手术切除前的心血管功能恢复

Pheochromocytoma-induced cardiogenic shock requiring ECMO: cardiovascular recovery prior to surgical resection.

作者信息

Redler Toby Adrian, Mohtat-Nasri Zohra, Williams Brielle, Townend Philip

机构信息

Gold Coast University Hospital, Southport, Queensland, Australia

Gold Coast University Hospital, Southport, Queensland, Australia.

出版信息

BMJ Case Rep. 2024 Dec 15;17(12):e262827. doi: 10.1136/bcr-2024-262827.

Abstract

An otherwise healthy woman in her 30s presented with cardiogenic shock and acute pulmonary oedema (APO), subsequently requiring extracorporeal membrane oxygenation (ECMO). A CT scan revealed an adrenal mass that prompted the differential diagnosis of a pheochromocytoma crisis that was later further suggested by raised plasma metanephrines. In the absence of clear guidelines due to the clinical rarity, a decision was made to delay adrenalectomy and stabilise the patient from a cardiac perspective with the view to operate after improvement of cardiac function with adequate alpha and beta blockade. Despite multiple complications, the patient was discharged from the hospital on day 32. After stabilisation and improvement of cardiac function, the patient underwent laparoscopic adrenalectomy. She was haemodynamically stable throughout the operation and was discharged on postoperative day 1 from the ICU to home. Histology confirmed the diagnosis of pheochromocytoma. She has been stable on follow-up.

摘要

一名30多岁原本健康的女性出现心源性休克和急性肺水肿(APO),随后需要进行体外膜肺氧合(ECMO)治疗。CT扫描发现肾上腺肿块,这促使对嗜铬细胞瘤危象进行鉴别诊断,随后血浆间甲肾上腺素升高进一步提示了这一诊断。由于临床罕见,缺乏明确的指南,因此决定推迟肾上腺切除术,并从心脏角度稳定患者病情,以期在心脏功能改善且进行充分的α和β受体阻滞剂治疗后进行手术。尽管出现了多种并发症,患者在第32天出院。在心脏功能稳定并改善后,患者接受了腹腔镜肾上腺切除术。术中她的血流动力学稳定,术后第1天从重症监护病房出院回家。组织学检查确诊为嗜铬细胞瘤。随访期间她病情稳定。

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