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2021年日本斜视患者的治疗趋势。

2021 trends in the treatment of patients with strabismus in Japan.

作者信息

Kunimi Keiko, Goseki Toshiaki, Nishina Sachiko, Negishi Takashi, Sato Miho

机构信息

Department of Ophthalmology, International University of Health and Welfare, Atami Hospital, 13-1 Higashi-kaigan-cho, Atami-City, Shizuoka, 413-0012, Japan.

Department of Ophthalmology, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.

出版信息

Jpn J Ophthalmol. 2025 Jan;69(1):10-16. doi: 10.1007/s10384-024-01144-5. Epub 2024 Dec 16.

Abstract

PURPOSE

To clarify the actual status of strabismus surgery and botulinum toxin (BTX) therapy in Japan in the year 2021.

STUDY DESIGN

Cross-sectional study.

METHODS

We conducted a national survey of strabismus treatment in 2021 using a questionnaire consistent with a previous 2013 survey, incorporating additional questions about BTX therapy.

RESULTS

Among the 378 responding institutions, strabismus surgery or BTX therapy, or both, was performed at 185 institutions (49%; total cases, 10,767). In 151 (40%), 32 (8%), and 2 (1%) institutions, surgery only, surgery and BTX therapy, and BTX therapy only were performed, respectively. The distribution of institutions where strabismus surgery was performed consisted of 4 prefectures, accounting for 48% of the total, whereas no strabismus surgery was performed at any institution in 3 prefectures. Although the highest percentage of patients (23%) was aged between 10 and 19 years, 48.2% of the patients were aged 20 years or older, and 17% of them were aged 60 years or older. Exotropia (XT) was the most common type of strabismus (55%) followed by esotropia (ET) (24%). In terms of complex surgeries, 80.2% (more than 100 cases) were performed at institutions with more than 100 cases. Of the 34 institutions where BTX therapy was performed, 52% were performed at a single institution, and 18% were performed at 2 institutions where no strabismus surgery was performed. Patients with scarring in the extraocular muscles, such as thyroid eye disease, were the most treated, followed by those with ET, who were mainly given injection treatment.

CONCLUSION

Institutions where strabismus surgery and BTX therapy could be performed were concentrated and limited.

摘要

目的

阐明2021年日本斜视手术和肉毒杆菌毒素(BTX)治疗的实际情况。

研究设计

横断面研究。

方法

我们采用与2013年之前的调查一致的问卷对2021年的斜视治疗进行了全国性调查,并纳入了有关BTX治疗的额外问题。

结果

在378家回复机构中,185家机构(49%;总病例数为10767例)进行了斜视手术或BTX治疗,或两者皆有。仅进行手术、手术和BTX治疗、仅进行BTX治疗的机构分别有151家(40%)、32家(8%)和2家(1%)。进行斜视手术的机构分布在4个县,占总数的48%,而3个县的任何机构都未进行斜视手术。尽管患者比例最高的年龄段(23%)为10至19岁,但48.2%的患者年龄在20岁及以上,其中17%的患者年龄在60岁及以上。外斜视(XT)是最常见的斜视类型(55%),其次是内斜视(ET)(24%)。在复杂手术方面,80.2%(超过100例)在病例数超过100例的机构进行。在进行BTX治疗的34家机构中,52%在单一机构进行,18%在2家未进行斜视手术的机构进行。眼外肌有瘢痕形成的患者,如甲状腺眼病患者,接受治疗的最多,其次是内斜视患者,主要接受注射治疗。

结论

能够进行斜视手术和BTX治疗的机构集中且有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aba/11821698/8c8a0b0c5bb1/10384_2024_1144_Fig1_HTML.jpg

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