Yang Isabelle T, Tung Avery, Flores Kelsey S, Berenhaut Kenneth S, Choi Jungbin A, Bryan Yvon F
From the Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Anesth Analg. 2025 Feb 1;140(2):295-305. doi: 10.1213/ANE.0000000000007049. Epub 2024 Dec 17.
Difficult airway management (DAM) is a challenging aspect of anesthetic care. Although nearly all DAM episodes result in successful intubation, complications are common and clinical decision-making may be complex. In adults with anticipated DAM scheduled for nonemergent surgery, we prospectively observed clinical decisions made during DAM such as awake/sedated versus anesthetized, choice of initial and subsequent devices, case cancellation/postponement, conversions between awake and anesthetized approaches, and process complications such as multiple intubation/supraglottic airway (SGA) insertion attempts, difficult bag-mask ventilation (BMV), hypoxemia, and cardiovascular destabilization.
From 2009 to 2014, we prospectively observed 1295 episodes of anticipated DAM in a convenience sample of 1245 adults scheduled for nonemergent surgery. Trained observers recorded airway management decisions and process complications during DAM. We described clinical decisions made during DAM and outcomes including number of attempts, need for BMV, hypoxemia, and cardiovascular destabilization.
No cases were canceled/postponed for airway management failure and all intubations were eventually successful. Of the 1295 episodes of airway management in our study cohort, 166 (13%) were intubated awake. Patients intubated awake had more difficult airway indicators than those intubated anesthetized, their first-pass success rate was 49%, 30% required ≥3 attempts, 4% required a device change, 50% experienced hypoxemia, and 29% experienced cardiovascular destabilization. Among the 1129 patients intubated while anesthetized, first-pass success rate was 64% and 20% required ≥3 attempts, 11% required a device change, hypoxemia occurred in 30%, and cardiovascular destabilization in 20%. One patient (0.08%) was converted from an anesthetized to an awake approach. Patients with a failed anesthetized intubation attempt and difficult BMV between attempts were at high risk for multiple attempts (67%) and hypoxemia (100%).
Airway management was successful in all patients and the incidence of process complications was higher than in routine airway management. Despite a high risk of DAM, 87% of patients were intubated anesthetized and conversions between awake and anesthetized approaches were rare. That patients intubated awake had more difficult airway indicators implies that clinicians reserve awake intubation for particularly difficult airways. The high incidence of multiple attempts, hypoxemia, and cardiovascular destabilization in patients intubated awake suggests that awake airway management remains challenging. We found no clear pattern in device choices after a first failed attempt. Patients with a first failed anesthetized intubation attempt and difficult BMV were at particularly high risk for hypoxemia.
困难气道管理(DAM)是麻醉护理中具有挑战性的一个方面。尽管几乎所有的DAM情况最终都能成功插管,但并发症很常见,临床决策可能也很复杂。对于计划进行非急诊手术且预计有DAM的成年患者,我们前瞻性地观察了DAM期间做出的临床决策,如清醒/镇静与麻醉状态下的决策、初始及后续设备的选择、病例取消/延期、清醒与麻醉方法之间的转换,以及诸如多次插管/声门上气道(SGA)插入尝试、困难面罩通气(BMV)、低氧血症和心血管不稳定等过程并发症。
2009年至2014年,我们对1245例计划进行非急诊手术的成年患者的便利样本中的1295例预期DAM情况进行了前瞻性观察。训练有素的观察者记录了DAM期间的气道管理决策和过程并发症。我们描述了DAM期间做出的临床决策及结果,包括尝试次数、BMV需求、低氧血症和心血管不稳定情况。
没有因气道管理失败而取消/延期的病例,所有插管最终均成功。在我们的研究队列中的1295例气道管理情况中,166例(13%)在清醒状态下插管。清醒插管的患者比麻醉状态下插管的患者有更多困难气道指标,其首次插管成功率为49%,30%的患者需要≥3次尝试,4%的患者需要更换设备,50%的患者出现低氧血症,29%的患者出现心血管不稳定。在1129例麻醉状态下插管的患者中,首次插管成功率为64%,20%的患者需要≥3次尝试,11%的患者需要更换设备,30%的患者出现低氧血症,20%的患者出现心血管不稳定。1例患者(0.08%)从麻醉方法转换为清醒方法。麻醉插管尝试失败且两次尝试之间BMV困难的患者多次尝试(67%)和低氧血症(100%)的风险很高。
所有患者的气道管理均成功,过程并发症的发生率高于常规气道管理。尽管DAM风险很高,但87%的患者在麻醉状态下插管,清醒与麻醉方法之间的转换很少见。清醒插管的患者有更多困难气道指标,这意味着临床医生将清醒插管保留用于特别困难的气道。清醒插管患者中多次尝试、低氧血症和心血管不稳定的发生率很高,这表明清醒气道管理仍然具有挑战性。首次尝试失败后,我们在设备选择上未发现明确模式。首次麻醉插管尝试失败且BMV困难的患者发生低氧血症的风险特别高。