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老年和非老年成年人因退行性腰椎病变接受全内镜脊柱手术后疼痛及功能结果的比较。

Comparison of Pain and Functional Outcomes Among Geriatric and Nongeriatric Adults Following Full Endoscopic Spine Surgery for Degenerative Lumbar Pathology.

作者信息

Chernysh Alexander A, Leyendecker Jannik, Leary Owen P, Sastry Rahul A, Gokaslan Ziya L, Fridley Jared S, Derman Peter, Kashlan Osama, Konakondla Sanjay, Ogunlade John, Hofstetter Christoph P, Telfeian Albert E

机构信息

Department of Neurosurgery, Warren Alpert Medical School, Brown University, Providence, RI, USA

Department of Neurological Surgery, University of Washington, Seattle, WA, USA.

出版信息

Int J Spine Surg. 2025 Mar 6;19(1):27-38. doi: 10.14444/8693.

DOI:10.14444/8693
PMID:39689970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12053108/
Abstract

BACKGROUND

Full endoscopic spine surgery (FESS) champions a rapid recovery and a low rate of overall complications. However, its efficacy in geriatric patients that might yield additional benefits from minimized invasiveness remains underexplored.

METHODS

A multi-institutional prospective cohort study was conducted involving patients undergoing elective lumbar FESS. Participants were categorized into nongeriatric (18-69 years old) and geriatric (≥70 years old) groups. Studied variables included demographics, medical comorbidities, operative details, visual analog scale (VAS) for back and leg pain, and Oswestry Disability Index (ODI). A mobile application was leveraged to collect real-time data pre- and postoperatively.

RESULTS

One hundred and sixty-four patients were included and divided into nongeriatric ( = 125) and geriatric ( = 39) cohorts. No group differences were observed between sex ( = 0.404), body mass index ( = 0.372), procedure duration ( = 0.350), or blood loss ( = 0.384). Nongeriatric patients received discectomy more frequently ( < 0.001), while older patients underwent more decompressive procedures ( < 0.001). Characterization of pain and functional outcome revealed that nongeriatric and geriatric patients follow a similar recovery trajectory and both appreciate significant improvements from baseline to 3 months postoperatively ( < 0.001 for VAS back, VAS leg, and ODI). There were no differences in the rate of improvement between age groups at any time point ( > 0.05 for VAS back, VAS leg, and ODI).

CONCLUSIONS

FESS significantly improves pain and function in both geriatric and nongeriatric adults with degenerative lumbar conditions, with no difference in the degree of improvement between groups.

CLINICAL RELEVANCE

These findings underscore the efficacy of FESS as a minimally invasive surgical option for elderly patients. Mobile application technology is useful for collecting patient-reported data in spine surgery clinical research.

摘要

背景

全内镜脊柱手术(FESS)支持快速康复且总体并发症发生率低。然而,其在老年患者中的疗效尚未得到充分探索,而老年患者可能会从微创中获得额外益处。

方法

进行了一项多机构前瞻性队列研究,纳入接受择期腰椎FESS的患者。参与者被分为非老年组(18 - 69岁)和老年组(≥70岁)。研究变量包括人口统计学、合并症、手术细节、背部和腿部疼痛的视觉模拟量表(VAS)以及Oswestry功能障碍指数(ODI)。利用移动应用程序收集术前和术后的实时数据。

结果

共纳入164例患者,分为非老年组(n = 125)和老年组(n = 39)队列。在性别(P = 0.404)、体重指数(P = 0.372)、手术时长(P = 0.350)或失血量(P = 0.384)方面未观察到组间差异。非老年患者更频繁地接受椎间盘切除术(P < 0.001),而老年患者接受更多减压手术(P < 0.001)。疼痛和功能结果的特征表明,非老年和老年患者遵循相似的恢复轨迹,且从基线到术后3个月均有显著改善(VAS背部、VAS腿部和ODI的P < 0.001)。在任何时间点,年龄组之间的改善率均无差异(VAS背部 VAS腿部和ODI的P > 0.05)。

结论

FESS显著改善了患有退行性腰椎疾病的老年和非老年成年人的疼痛和功能,两组之间的改善程度无差异。临床意义:这些发现强调了FESS作为老年患者微创外科手术选择的疗效。移动应用技术有助于在脊柱手术临床研究中收集患者报告的数据。

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本文引用的文献

1
Smartphone applications for remote patient monitoring reduces clinic utilization after full-endoscopic spine surgery.用于远程患者监测的智能手机应用程序可降低全内镜脊柱手术后的门诊利用率。
J Telemed Telecare. 2024 Feb 6:1357633X241229466. doi: 10.1177/1357633X241229466.
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Pain alleviation and functional improvement: ultra-early patient-reported outcome measures after full endoscopic spine surgery.疼痛缓解与功能改善:全内镜脊柱手术后超早期患者报告结局测量
J Neurosurg Spine. 2024 Jan 5;40(4):465-474. doi: 10.3171/2023.11.SPINE231048. Print 2024 Apr 1.
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Assessing the impact of obesity on full endoscopic spine surgery: surgical site infections, surgery durations, early complications, and short-term functional outcomes.评估肥胖对全内镜脊柱手术的影响:手术部位感染、手术时长、早期并发症及短期功能结局。
J Neurosurg Spine. 2023 Dec 8;40(3):359-364. doi: 10.3171/2023.10.SPINE23936. Print 2024 Mar 1.
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The Current Status of Awake Endoscopic Surgery: A Systematic Review and Meta-Analysis.清醒内镜手术的现状:系统评价和荟萃分析。
World Neurosurg. 2023 Dec;180:e198-e209. doi: 10.1016/j.wneu.2023.09.023. Epub 2023 Sep 14.
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Comparative analysis of perioperative characteristics and early outcomes in transforaminal endoscopic lumbar diskectomy: general anesthesia versus conscious sedation.经椎间孔内镜腰椎间盘切除术围手术期特征及早期结局的比较分析:全身麻醉与清醒镇静的对比
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Efficacy of Transforaminal Endoscopic Lumbar Discectomy in Elderly Patients Over 65 Years of Age Compared to Young Adults.与年轻成年人相比,经椎间孔内镜下腰椎间盘切除术治疗65岁以上老年患者的疗效
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Efficacy and safety of percutaneous transforaminal endoscopic surgery (PTES) compared with MIS-TLIF for surgical treatment of lumbar degenerative disease in elderly patients: A retrospective cohort study.经皮椎间孔镜手术(PTES)与微创经椎间孔腰椎椎体间融合术(MIS-TLIF)治疗老年腰椎退行性疾病的疗效及安全性比较:一项回顾性队列研究
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