Gan Jinjing, Zhang Chuanzhi, Tang Dagang, Du Xing
Department of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400021, China.
Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, No.1 YouYi Road, Yuanjiagang, Yu Zhong District, Chongqing, 400016, China.
Eur J Med Res. 2024 Dec 18;29(1):588. doi: 10.1186/s40001-024-02198-4.
Tuberculosis (TB) is a worldwide disease which seriously affects the global public health. Spinal TB is the most common extra-pulmonary TB and may cause vertebral bone destruction, collapse, kyphosis and even paralysis. Anti-TB chemotherapy is considered the cornerstone treatment of spinal TB and surgery is often required for patients with severe kyphosis, impaired neurological function or spinal instability. Debridement of TB lesions, bone grafting and internal fixation are the key procedures of spinal TB surgery. However, the selection of surgical approach, the extent of TB lesion debridement, the choice of bone graft materials, and the method and extent of internal fixation are all remain controversy. The aim of this updated review is to evaluate current literature for advances in management of spinal TB, with particular focus on surgical techniques.
结核病（TB）是一种全球性疾病，严重影响全球公共卫生。脊柱结核是最常见的肺外结核，可导致椎体骨质破坏、塌陷、脊柱后凸甚至瘫痪。抗结核化疗被认为是脊柱结核的基础治疗方法，对于严重脊柱后凸、神经功能受损或脊柱不稳定的患者通常需要进行手术。结核病灶清除、植骨和内固定是脊柱结核手术的关键步骤。然而，手术入路的选择、结核病灶清除的范围、植骨材料的选择以及内固定的方法和范围仍存在争议。这篇更新综述的目的是评估当前关于脊柱结核治疗进展的文献，特别关注手术技术。
