Hietanen T, Nieminen S, Ekfors T, Nordman E
Strahlentherapie. 1985 Jan;161(1):1-4.
Malignant melanoma of Clark level II to V was studied in 96 patients. An elective dissection or elective irradiation of the regional lymph nodes was performed in 45 patients, whereas 51 patients were not treated electively. No statistically significant differences were observed as to the survival or recurrence-free time in the regional lymph nodes in either of these two patient groups. Between the patient groups with or without selective treatment, there was not any significant difference either, even when the prognosis and recurrence of the patients were correlated to the invasion level of the primary melanoma according to Clark or Breslow.
对96例Clark II至V级恶性黑色素瘤患者进行了研究。45例患者进行了区域淋巴结选择性清扫或选择性放疗,而51例患者未进行选择性治疗。在这两组患者中,区域淋巴结的生存率或无复发生存时间均未观察到统计学上的显著差异。在接受或未接受选择性治疗的患者组之间,即使根据Clark或Breslow将患者的预后和复发与原发性黑色素瘤的浸润水平相关联,也没有任何显著差异。