埃及一家三级眼科护理中心的耐药性角膜溃疡：10年流行病学研究
Resistant corneal ulcers in a tertiary care ophthalmic center in Egypt: 10 years epidemiological study.
作者信息
Khater Mohammad M, Nassef Mohammad Hosny, Elshorbagy Mohamed Sameh
机构信息
Ophthalmology Department, Tanta University Hospital, Gharbia Governorate 31527, Egypt.
出版信息
Int J Ophthalmol. 2024 Dec 18;17(12):2282-2287. doi: 10.18240/ijo.2024.12.17. eCollection 2024.
AIM
To investigate the magnitude of problem caused by resistant corneal ulcers and its epidemiological characteristics.
METHODS
Patients with corneal lesions were selected and carefully examined and cases with resistant corneal ulcers were further investigated and data were recorded using a specific data sheet designed in hospital. Then, collected data from patients were statistically analyzed.
RESULTS
Totally 1939 cases were included in the study, including 816 fungal cases (42.1%) and 1123 (57.9%) non-fungal cases. Age of the participants ranged from 18 to 73y. Fungal cases were more common in middle age (35-55y). Men were more affected (53.5%) of cases included in the study. Keratomycosis affected more unskilled personnel (75.1%), large families with small houses (higher crowding index 73.9%), rural (64.5%) residence. Patients with sanitary water sources (34.8%) and waste disposal (24.4%) were less affected.
CONCLUSION
Keratomycosis is more frequent in unskilled personnel, rural locations, outdoor water sources and insanitary waste disposal systems. Corneal trauma and contact lens are common risk factors.
目的
探讨耐药性角膜溃疡所致问题的严重程度及其流行病学特征。
方法
选取角膜病变患者进行仔细检查，对耐药性角膜溃疡病例进一步调查，并使用医院设计的特定数据表记录数据。然后，对收集到的患者数据进行统计分析。
结果
本研究共纳入1939例病例，其中真菌性病例816例（42.1%），非真菌性病例1123例（57.9%）。参与者年龄在18至73岁之间。真菌性病例在中年（35 - 55岁）更为常见。男性受影响更多（占纳入研究病例的53.5%）。角膜真菌病在非技术人员中影响更大（75.1%），在房屋较小的大家庭（拥挤指数较高，73.9%）、农村地区（64.5%）更为常见。有卫生水源（34.8%）和废物处理设施（24.4%）的患者受影响较小。
结论
角膜真菌病在非技术人员、农村地区、户外水源和不卫生的废物处理系统中更为常见。角膜外伤和隐形眼镜是常见的危险因素。
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