Yassari Fatemeh, Khoundabi Batoul, Rashid Farokhi Farin, Mishra Rajesh Chandra, Jahan Lopa Ahsina, Hashemian Seyed MohammadReza
Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran-Helal Institute of Applied Science and Technology, Red Crescent Society of the Islamic Republic of Iran, Tehran, Iran.
Tanaffos. 2024 Jan;23(1):38-43.
Acute kidney injury (AKI) requires continuous renal replacement therapy (CRRT), which is one of the most important problems in medical and surgical patients. Therefore, it is very important to identify the influencing factors to reduce the dimensions of the problem. This study was conducted to investigate the mortality rate in medical and surgical patients with AKI requiring CRRT treatment.
In this observational study, which was conducted as a cross- sectional analytical study, 100 patients with AKI requiring CRRT treatment, including medical and surgical patients, were selected from 2018 to 2021 at Masih Daneshvari Hospital. The mortality rate was estimated. Also, the effective factors were investigated and compared between the dead and surviving patients.
85 cases (85%) of the patients died. Most underlying and demographic variables had no statistically significant difference between the dead and surviving patients (P>0.05). However, in the cases of primary calcium (P=0.001), primary leukocyte (P=0.037), bicarbonate during hospitalization (P=0.025), bicarbonate during AKI (P=0.028), magnesium during hospitalization (P=0.038), and magnesium at the end of CRRT (P=0.019), the differences were statistically significant.
In conclusion, mortality is observed in 5 out of 6 patients with acute kidney failure who need CRRT treatment, which is related to risk factors such as bicarbonate, magnesium, leukocyte, and calcium levels. Therefore, multifaceted planning is needed to reduce its dimensions to improve the prognosis of this group of patients.
急性肾损伤（AKI）需要持续肾脏替代治疗（CRRT），这是内科和外科患者面临的最重要问题之一。因此，识别影响因素以缩小问题规模非常重要。本研究旨在调查需要CRRT治疗的内科和外科AKI患者的死亡率。
本观察性研究采用横断面分析研究方法，于2018年至2021年在马西·达内什瓦里医院选取了100例需要CRRT治疗的AKI患者，包括内科和外科患者。估算死亡率。此外，还对死亡患者和存活患者的影响因素进行了调查和比较。
85例（85%）患者死亡。大多数基础和人口统计学变量在死亡患者和存活患者之间无统计学显著差异（P>0.05）。然而，在原发性钙（P=0.001）、原发性白细胞（P=0.037）、住院期间碳酸氢盐（P=0.025）、急性肾损伤期间碳酸氢盐（P=0.028）、住院期间镁（P=0.038）和CRRT结束时镁（P=0.019）方面，差异具有统计学显著性。
总之，在6例需要CRRT治疗的急性肾衰竭患者中，有5例观察到死亡，这与碳酸氢盐、镁、白细胞和钙水平等危险因素有关。因此，需要进行多方面规划以缩小其规模，从而改善这组患者的预后。
