Conrad Paige, John Jennifer, De Lemos Andrea, Biglione Alejandro
Internal Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Internal Medicine, Wellington Regional Medical Center, Wellington, USA.
Cureus. 2024 Nov 19;16(11):e73995. doi: 10.7759/cureus.73995. eCollection 2024 Nov.
Posterior reversible encephalopathy syndrome (PRES) is a neurologic condition defined by symptoms and imaging findings secondary to vasogenic edema in the brain. Even though not all hypertensive individuals will progress to PRES, high blood pressure is the most frequent risk factor associated with the condition. The pathophysiology of PRES is not clearly understood, but the most accepted proposed mechanism focuses on the brain's inability to regulate cerebral blood flow through constriction or dilation of vessels during extreme blood pressure. This case report is about a 38-year-old male patient who presented to the hospital complaining of a headache and was found to have severe hypertension associated with PRES and a pontine infarct. The epidemiology, etiology, pathophysiologic mechanism, clinical presentation, radiologic findings, management, and prognosis of PRES syndrome are discussed.
后部可逆性脑病综合征(PRES)是一种神经系统疾病,由脑部血管源性水肿继发的症状和影像学表现所定义。尽管并非所有高血压患者都会发展为PRES,但高血压是与该疾病相关的最常见危险因素。PRES的病理生理学尚不清楚,但最被认可的机制认为,在血压极端波动时,大脑无法通过血管收缩或扩张来调节脑血流量。本病例报告讲述的是一名38岁男性患者,因头痛入院,被发现患有与PRES相关的严重高血压和脑桥梗死。文中还讨论了PRES综合征的流行病学、病因、病理生理机制、临床表现、影像学表现、治疗及预后。