Hisata Yoichi, Taguchi Shunsuke, Shintomi Masahisa, Koga Yasuaki, Yamada Takafumi
Division of Cardiovascular Surgery, Oita Prefectural Hospital, Japan.
Division of Cardiology, Oita Prefectural Hospital, Japan.
Intern Med. 2025 Jul 1;64(13):2002-2006. doi: 10.2169/internalmedicine.4571-24. Epub 2024 Dec 26.
Non-bacterial thrombotic endocarditis (NBTE) causes myocardial and cerebral infarctions and is associated with advanced stages of malignancy. However, only a few cases of myocardial and cerebral infarctions have been reported in the same patient. We herein report a 47-year-old woman with advanced uterine and ovarian cancer who experienced acute myocardial infarction (MI) after receiving chemotherapeutic intervention for the cancer and hemorrhagic cerebral infarction 1 month after admission for acute MI, attributable to NBTE of the aortic valve. NBTE should be considered in patients with malignancies and life-threatening thromboembolism of important organs.
非细菌性血栓性心内膜炎(NBTE)可导致心肌梗死和脑梗死,并与恶性肿瘤的晚期阶段相关。然而,同一患者同时发生心肌梗死和脑梗死的病例仅有少数报道。我们在此报告一名47岁患有晚期子宫和卵巢癌的女性,在接受癌症化疗干预后发生急性心肌梗死(MI),在因急性MI入院1个月后发生出血性脑梗死,这归因于主动脉瓣的NBTE。对于患有恶性肿瘤且出现重要器官危及生命的血栓栓塞的患者,应考虑NBTE。