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晚期子宫和卵巢癌患者继发非细菌性血栓性心内膜炎的急性心肌梗死和出血性脑梗死

Acute Myocardial and Hemorrhagic Cerebral Infarction Secondary to Non-bacterial Thrombotic Endocarditis in a Patient with Advanced Uterine and Ovarian Cancer.

作者信息

Hisata Yoichi, Taguchi Shunsuke, Shintomi Masahisa, Koga Yasuaki, Yamada Takafumi

机构信息

Division of Cardiovascular Surgery, Oita Prefectural Hospital, Japan.

Division of Cardiology, Oita Prefectural Hospital, Japan.

出版信息

Intern Med. 2025 Jul 1;64(13):2002-2006. doi: 10.2169/internalmedicine.4571-24. Epub 2024 Dec 26.

Abstract

Non-bacterial thrombotic endocarditis (NBTE) causes myocardial and cerebral infarctions and is associated with advanced stages of malignancy. However, only a few cases of myocardial and cerebral infarctions have been reported in the same patient. We herein report a 47-year-old woman with advanced uterine and ovarian cancer who experienced acute myocardial infarction (MI) after receiving chemotherapeutic intervention for the cancer and hemorrhagic cerebral infarction 1 month after admission for acute MI, attributable to NBTE of the aortic valve. NBTE should be considered in patients with malignancies and life-threatening thromboembolism of important organs.

摘要

非细菌性血栓性心内膜炎(NBTE)可导致心肌梗死和脑梗死,并与恶性肿瘤的晚期阶段相关。然而,同一患者同时发生心肌梗死和脑梗死的病例仅有少数报道。我们在此报告一名47岁患有晚期子宫和卵巢癌的女性,在接受癌症化疗干预后发生急性心肌梗死(MI),在因急性MI入院1个月后发生出血性脑梗死,这归因于主动脉瓣的NBTE。对于患有恶性肿瘤且出现重要器官危及生命的血栓栓塞的患者,应考虑NBTE。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa01/12287591/cba08b3798fb/1349-7235-64-13-2002-g001.jpg

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