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解读关联：揭示肠道微生物群在纤维肌痛中的作用。

Decoding the connection: unraveling the role of gut microbiome in fibromyalgia.

作者信息

Minerbi Amir, Khoutorsky Arkady, Shir Yoram

机构信息

Rambam Health Campus, Haifa, Israel.

Ruth and Bruce Rapaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.

出版信息

Pain Rep. 2024 Dec 24;10(1):e1224. doi: 10.1097/PR9.0000000000001224. eCollection 2025 Feb.

DOI:10.1097/PR9.0000000000001224
PMID:39726854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11671092/
Abstract

The gut microbiome is emerging as a critical player in the pathophysiology of fibromyalgia, offering mechanistic insights as well as potential diagnostic and therapeutic applications.

摘要

肠道微生物群正在成为纤维肌痛病理生理学中的关键因素，为其提供了机制性见解以及潜在的诊断和治疗应用。

相似文献

[1]
Decoding the connection: unraveling the role of gut microbiome in fibromyalgia.

Pain Rep. 2024-12-24

[2]
Uncovering the Hidden Link Between the Aberrant Intestinal Microbiome and Fibromyalgia.

Gastroenterol Hepatol (N Y). 2025-3

[3]
Altered serum bile acid profile in fibromyalgia is associated with specific gut microbiome changes and symptom severity.

Pain. 2023-2-1

[4]
Gut microbiome: pertinence in fibromyalgia.

Clin Exp Rheumatol. 2020-2-12

[5]
The gut microbiota promotes pain in fibromyalgia.

Neuron. 2025-7-9

[6]
Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia.

EBioMedicine. 2019-7-18

[7]
Fibromyalgia-associated hyperalgesia is related to psychopathological alterations but not to gut microbiome changes.

PLoS One. 2022

[8]
Unraveling mechanistic insights into the role of microbiome in neurogenic hypertension: A comprehensive review.

Pathol Res Pract. 2023-9

[9]
Determining the association between fibromyalgia, the gut microbiome and its biomarkers: A systematic review.

BMC Musculoskelet Disord. 2020-3-20

[10]
Unraveling the Complex Web of Fibromyalgia: A Narrative Review.

Medicina (Kaunas). 2024-2-4

引用本文的文献

[1]
Fibromyalgia, more than "just pain".

Pain Manag. 2025-7

[2]
Neuroinflammatory and Immunological Aspects of Fibromyalgia.

Brain Sci. 2025-2-17

本文引用的文献

[1]
Fecal Microbiota Transplantation Improves Clinical Symptoms of Fibromyalgia: An Open-Label, Randomized, Nonplacebo-Controlled Study.

J Pain. 2024-9

[2]
Small fibre pathology, small fibre symptoms and pain in fibromyalgia syndrome.

Sci Rep. 2024-2-16

[3]
Associations Between Brain-Gut Axis and Psychological Distress in Fibromyalgia: A Microbiota and Magnetic Resonance Imaging Study.

J Pain. 2024-4

[4]
Efficacy of a gluten-free diet in reducing the widespread pain index and symptom severity scale in patients affected by fibromyalgia.

Reumatismo. 2023-9-18

[5]
Dietary Implications of the Bidirectional Relationship between the Gut Microflora and Inflammatory Diseases with Special Emphasis on Irritable Bowel Disease: Current and Future Perspective.

Nutrients. 2023-6-29

[6]
Fibromyalgia and Irritable Bowel Syndrome Interaction: A Possible Role for Gut Microbiota and Gut-Brain Axis.

Biomedicines. 2023-6-13

[7]
Neutrophils infiltrate sensory ganglia and mediate chronic widespread pain in fibromyalgia.

Proc Natl Acad Sci U S A. 2023-4-25

[8]
Fibromyalgia patients with elevated levels of anti-satellite glia cell immunoglobulin G antibodies present with more severe symptoms.

Pain. 2023-8-1

[9]
The microbiota-gut-brain axis in sleep disorders.

Sleep Med Rev. 2022-10

[10]
Bile acids in immunity: Bidirectional mediators between the host and the microbiota.

Front Immunol. 2022

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