Hassan Muhammad, Vinagolu-Baur Julia, Li Vivian, Frasier Kelly, Herrick Grace, Scotto Tiffany, Rankin Erica
Department of Medicine, Nuvance Health, Vassar Brothers Medical Center, Poughkeepsie, NY 12601, United States.
Department of Medical Education, State University of New York, Upstate Medical University, Syracuse, NY 13210, United States.
World J Cardiol. 2024 Dec 26;16(12):707-719. doi: 10.4330/wjc.v16.i12.707.
Recent studies have suggested an evolving understanding of the association between vaping, specifically electronic cigarette (e-cigarette) use, and the progression of atherosclerosis, a significant contributor to cardiovascular disease. Despite the prevailing perception of vaping as a safer alternative to traditional tobacco smoking, accumulating evidence suggests that the aerosols emitted by e-cigarettes contain harmful constituents that may promote endothelial dysfunction, oxidative stress, inflammation, and dyslipidemia-key mechanisms implicated in atherosclerosis pathogenesis. While past research, including experimental studies and clinical investigations, has shed light on the potential cardiovascular risks associated with vaping, gaps in knowledge persist. Future research endeavors should focus on interpreting the long-term effects of vaping on atherosclerosis development and progression, exploring the impact of different e-cigarette formulations and user demographics, and identifying effective strategies for mitigating the cardiovascular consequences of vaping. By identifying and addressing these research gaps, we can enhance our understanding of the cardiovascular implications of vaping and inform evidence-based interventions and policies to safeguard public health.
最近的研究表明，人们对电子烟（尤其是使用电子烟）与动脉粥样硬化进展之间的关联的理解正在不断演变，动脉粥样硬化是心血管疾病的一个重要成因。尽管目前普遍认为电子烟是比传统吸烟更安全的替代品，但越来越多的证据表明，电子烟产生的气溶胶含有有害成分，可能会促进内皮功能障碍、氧化应激、炎症和血脂异常，这些都是动脉粥样硬化发病机制中的关键机制。虽然过去的研究，包括实验研究和临床调查，已经揭示了与使用电子烟相关的潜在心血管风险，但知识空白仍然存在。未来的研究应致力于解读使用电子烟对动脉粥样硬化发展和进展的长期影响，探索不同电子烟配方和用户特征的影响，并确定减轻使用电子烟对心血管影响的有效策略。通过识别和填补这些研究空白，我们可以加深对使用电子烟对心血管影响的理解，并为基于证据的干预措施和政策提供信息，以保障公众健康。
