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两性畸形病例的性别指定

Sex Assignment in Cases of Ambiguous Genitalia.

作者信息

Mohammed Hajira, Ansari Nesa, Baig Ahmed Zafar, Alshowaikhat Joud J, Uz Zama Madiha M, Hussain Timraz Jumana, Ahmed Ruqayyah A, Samy Mohommad

机构信息

Department of Medicine and Surgery, Batterjee Medical College for Science and Technology, Jeddah, SAU.

Department of General Surgery, General Medicine Practice Program, Batterjee Medical College for Science and Technology, Jeddah, SAU.

出版信息

Cureus. 2024 Nov 29;16(11):e74730. doi: 10.7759/cureus.74730. eCollection 2024 Nov.

Abstract

Ambiguous genitalia is a rare disorder where it is unclear whether an infant's external genitals are male or female. This can be attributed to various internal and external etiologies, such as androgen receptor abnormalities, gonadal abnormalities (such as gonadal dysgenesis or Klinefelter syndrome where a male has an extra X chromosome), enzymatic defects, etc. Correction of such atypical genitalia requires a multidisciplinary approach, including but not limited to surgeons and therapists. It is important to keep in mind that the treatment plan is tailored according to the specific etiology that is causative of the patient's condition, along with the anticipated perioperative and postoperative complications. Islamically speaking, this topic has been addressed in various Islamic literature and disciplines, including guidelines for dealing with this medical condition. Moreover, follow-up of the patient must be done to allow smooth integration into society.

摘要

两性畸形是一种罕见的病症,婴儿的外生殖器难以明确界定为男性或女性。这可能归因于多种内部和外部病因,如雄激素受体异常、性腺异常(如性腺发育不全或克兰费尔特综合征,男性多一条X染色体)、酶缺陷等。矫正这种非典型生殖器需要多学科方法,包括但不限于外科医生和治疗师。重要的是要记住,治疗方案是根据导致患者病情的具体病因以及预期的围手术期和术后并发症量身定制的。从伊斯兰教角度来看,这个话题在各种伊斯兰文献和学科中都有涉及,包括处理这种病症的指导方针。此外,必须对患者进行随访,以使其顺利融入社会。

相似文献

1
Sex Assignment in Cases of Ambiguous Genitalia.两性畸形病例的性别指定
Cureus. 2024 Nov 29;16(11):e74730. doi: 10.7759/cureus.74730. eCollection 2024 Nov.
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Diagnostic approach to the newborn with ambiguous genitalia.对生殖器模糊新生儿的诊断方法。
Pediatr Clin North Am. 1987 Aug;34(4):1019-31. doi: 10.1016/s0031-3955(16)36300-3.
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Abnormalities of gonadal differentiation.性腺分化异常。
Baillieres Clin Endocrinol Metab. 1998 Apr;12(1):133-42. doi: 10.1016/s0950-351x(98)80512-0.

本文引用的文献

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The impact of culture on disclosure in differences of sex development.文化对性发育差异中信息披露的影响。
Semin Pediatr Surg. 2019 Oct;28(5):150840. doi: 10.1016/j.sempedsurg.2019.150840. Epub 2019 Sep 13.
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A Clinical Approach to Diagnosis of Ambiguous Genitalia.两性畸形诊断的临床方法
J Indian Assoc Pediatr Surg. 2019 Jul-Sep;24(3):162-169. doi: 10.4103/jiaps.JIAPS_70_18.

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