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Gene therapy targets the retina to treat eye disease.

作者信息

Arnold Carrie

机构信息

Science writer, Richmond, VA, USA.

出版信息

Nat Med. 2025 Jan;31(1):2-3. doi: 10.1038/s41591-024-03454-0.

DOI:10.1038/s41591-024-03454-0

PMID:39747687

Abstract

摘要

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Gene therapy targets the retina to treat eye disease.

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引用本文的文献

Angiopoietin-1 and Tie2-Based Dual Cell Therapy Enhances Antiangiogenic Barrier Function in a Retina-Mimetic Model for Neovascular Retinal Disease.

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Gene therapy targets the retina to treat eye disease.

作者信息

Arnold Carrie

机构信息

Science writer, Richmond, VA, USA.

出版信息

Nat Med. 2025 Jan;31(1):2-3. doi: 10.1038/s41591-024-03454-0.

DOI:10.1038/s41591-024-03454-0

PMID:39747687

Abstract

摘要

相似文献

Gene therapy targets the retina to treat eye disease.

Nat Med. 2025 Jan;31(1):2-3. doi: 10.1038/s41591-024-03454-0.

Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development.

Hum Mol Genet. 2001 Jul 15;10(15):1571-9. doi: 10.1093/hmg/10.15.1571.

Strengthening retina eye care services in Nepal: retina eye care of Nepal project.

BMC Health Serv Res. 2020 Oct 27;20(1):986. doi: 10.1186/s12913-020-05850-x.

Identification of regulatory targets of tissue-specific transcription factors: application to retina-specific gene regulation.

Nucleic Acids Res. 2005 Jun 20;33(11):3479-91. doi: 10.1093/nar/gki658. Print 2005.

Somatostatin receptor gene expression in human ocular tissues: RT-PCR and immunohistochemical study.

Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2193-201.

Gene delivery to the retina: focus on non-viral approaches.

Drug Discov Today. 2009 Mar;14(5-6):306-15. doi: 10.1016/j.drudis.2008.09.012. Epub 2008 Nov 13.

Ion Channels in the Eye: Involvement in Ocular Pathologies.

Adv Protein Chem Struct Biol. 2016;104:157-231. doi: 10.1016/bs.apcsb.2015.11.006. Epub 2015 Dec 31.

Retinal gene delivery by rAAV and DNA electroporation.

Curr Protoc Microbiol. 2013;Chapter 14:Unit 14D.4. doi: 10.1002/9780471729259.mc14d04s28.

Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues.

Exp Eye Res. 2018 Mar;168:57-68. doi: 10.1016/j.exer.2018.01.009. Epub 2018 Jan 11.

Eye formation in the absence of retina.

Dev Biol. 2008 Oct 1;322(1):56-64. doi: 10.1016/j.ydbio.2008.07.009. Epub 2008 Jul 16.

引用本文的文献

Angiopoietin-1 and Tie2-Based Dual Cell Therapy Enhances Antiangiogenic Barrier Function in a Retina-Mimetic Model for Neovascular Retinal Disease.

Tissue Eng Regen Med. 2025 Jul 21. doi: 10.1007/s13770-025-00739-4.