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植物毒素的植物化学指纹图谱作为法医学中揭示自然秘密的前沿方法。

Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature's secrets in forensic science.

作者信息

Zakaria Nabil, El-Sayed Ashraf S A, Ali Mostafa G

机构信息

Phytochemistry lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.

Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, 44519, Zagazig, Egypt.

出版信息

Nat Prod Bioprospect. 2025 Jan 3;15(1):1. doi: 10.1007/s13659-024-00484-6.

Abstract

The integration of phytochemistry into forensic science has emerged as a groundbreaking frontier, providing unprecedented insights into nature's secrets through the precise application of phytochemical fingerprinting of phytotoxins as a cutting-edge approach. This study explores the dynamic intersection of phytochemistry and forensic science, highlighting how the unique phytochemical profiles of toxic plants and their secondary metabolites, serve as distinctive markers for forensic investigations. By utilizing advanced techniques such as Ultra-High-Performance Liquid Chromatography (UHPLC) and High-Resolution Mass Spectrometry (HRMS), the detection and quantification of plant-derived are made more accurate in forensic contexts. Real-world case studies are presented to demonstrate the critical role of plant toxins in forensic outcomes and legal proceedings. The challenges, potential, and future prospects of integrating phytochemical fingerprinting of plant toxins into forensic science were discussed. This review aims to illuminate phytochemical fingerprinting of plant toxins as a promising tool to enhance the precision and depth of forensic analyses, offering new insights into the complex stories embedded in plant toxins.

摘要

植物化学与法医学的融合已成为一个开创性的前沿领域,通过将植物毒素的植物化学指纹图谱作为一种前沿方法进行精确应用,为洞察自然秘密提供了前所未有的视角。本研究探讨了植物化学与法医学的动态交叉点,强调有毒植物及其次生代谢产物独特的植物化学特征如何作为法医学调查的独特标志物。通过使用超高效液相色谱(UHPLC)和高分辨率质谱(HRMS)等先进技术,在法医学背景下对植物来源物质的检测和定量变得更加准确。本文展示了实际案例研究,以证明植物毒素在法医学结果和法律程序中的关键作用。讨论了将植物毒素的植物化学指纹图谱整合到法医学中的挑战、潜力和未来前景。本综述旨在阐明植物毒素的植物化学指纹图谱作为一种有前途的工具,可提高法医学分析的精度和深度,为植物毒素中蕴含的复杂情况提供新的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbca/11695570/671a2dc09833/13659_2024_484_Fig1_HTML.jpg

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