Nasso Giuseppe, Condello Ignazio, Vignaroli Walter, Antonazzo Andrea, Bartolomucci Francesco, Pala Barbara, Larosa Claudio, Pingitore Annachiara, Amodeo Vincenzo, Montemurro Vincenzo, D'Abramo Mizar, Ceravolo Roberto, Donato Domenica, Fratto Pasquale, De Rosis Maria Grazia, Diaferia Giuseppe, Torraco Rita, Contegiacomo Gaetano, Lembo Guido, Brigiani Mario Siro, Santarpino Giuseppe, Speziale Giuseppe
Department of Cardiovascular Surgery, GVM Care & Research, Anthea Hospital, Bari, Italy.
Anthea Hospital GVM Care & Research, Via Camillo Rosalba n 35, Bari, 70124, Italy.
Sci Rep. 2025 Jan 2;15(1):445. doi: 10.1038/s41598-024-84983-z.
Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence of post-MI VSD, likely driven by delays in seeking treatment. This study retrospectively analyzed 10 cases of post-MI VSD treated at our hospitals from March 2018 to August 2023, comparing incidence rates across pre-pandemic, pandemic, and post-pandemic periods. The findings revealed a notable increase in VSD cases during the pandemic, with six cases occurring in two years, compared to only two cases in each of the pre-pandemic and post-pandemic periods. Despite these fluctuations, surgical intervention remained a crucial and effective treatment, with 60% of patients surviving the 30-day follow-up. The study underscores the impact of delayed treatment on VSD incidence during the pandemic and highlights the critical need for timely medical intervention to manage severe MI complications effectively.
室间隔缺损（VSD）是心肌梗死（MI）的一种严重并发症，近年来由于冠状动脉再灌注技术的进步，其全球发病率显著降低。然而，在新冠疫情期间，心肌梗死后室间隔缺损的发病率意外上升，可能是由于就诊延迟所致。本研究回顾性分析了2018年3月至2023年8月在我院接受治疗的10例心肌梗死后室间隔缺损病例，比较了疫情前、疫情期间和疫情后各时期的发病率。研究结果显示，疫情期间室间隔缺损病例显著增加，两年内出现6例，而疫情前和疫情后各时期均仅为2例。尽管有这些波动，手术干预仍然是关键且有效的治疗方法，60%的患者在30天随访期内存活。该研究强调了疫情期间治疗延迟对室间隔缺损发病率的影响，并突出了及时进行医疗干预以有效管理严重心肌梗死并发症的迫切需求。
