Dourish C T
Pharmacol Biochem Behav. 1985 Jan;22(1):159-62. doi: 10.1016/0091-3057(85)90501-5.
The behavioural effects of bilateral injections of beta-phenylethylamine (PEA) into the caudate nucleus of male rats were examined. PEA in doses of 200 and 300 micrograms increased locomotion with maximal stimulation being evident 15-25 min after injection. In addition 300 micrograms PEA increased rearing 20-25 min post injection and produced increases in sniffing. This is the first report of a behavioural stimulant effect of intracranially administered PEA without concurrent monoamine oxidase inhibition. The data suggest that the stimulant action of systemically administered PEA may be mediated, at least in part, by striatal mechanisms.
研究了向雄性大鼠尾状核双侧注射β-苯乙胺（PEA）的行为效应。200和300微克剂量的PEA可增加运动能力，注射后15 - 25分钟刺激作用最为明显。此外，300微克PEA在注射后20 - 25分钟可增加竖毛行为，并使嗅探行为增加。这是首次报道颅内注射PEA在无单胺氧化酶抑制作用时的行为兴奋效应。数据表明，全身给药的PEA的兴奋作用可能至少部分由纹状体机制介导。
