Masuda Kyoko, Sakurai Masatoshi, Shiozawa Yuka, Sakamoto Miki, Shindo Takahide, Inokuchi Ami, Hayashi Hiroyoshi, Koda Yuya, Nagata Hiromasa, Kato Jun, Kataoka Keisuke
Division of Hematology, Department of Medicine, Keio University School of Medicine, Japan.
Department of Anesthesiology, Keio University School of Medicine, Japan.
Intern Med. 2025 Aug 1;64(15):2390-2393. doi: 10.2169/internalmedicine.4830-24. Epub 2025 Jan 3.
Phlegmonous gastritis (PG) is a rare, life-threatening bacterial infection characterized by thickening of the gastric wall. We report a case of PG in a 17-year-old male following allogeneic hematopoietic stem cell transplantation for severe aplastic anemia. Seven months after transplantation, the patient presented with severe abdominal pain, fever, and significant gastric wall thickening on CT. Initial antibiotic therapy was initiated immediately. The patient developed multiple organ failure; however, his condition rapidly improved with intensive care. After two weeks, the patient improved and was successfully discharged. This is the first report of PG after transplantation, highlighting the need for an early diagnosis and treatment.
蜂窝织炎性胃炎（PG）是一种罕见的、危及生命的细菌感染，其特征为胃壁增厚。我们报告一例17岁男性在接受异基因造血干细胞移植治疗严重再生障碍性贫血后发生PG的病例。移植后七个月，患者出现严重腹痛、发热，CT显示胃壁显著增厚。立即开始初始抗生素治疗。患者出现多器官功能衰竭；然而，经过重症监护，其病情迅速改善。两周后，患者病情好转并成功出院。这是移植后发生PG的首例报告，强调了早期诊断和治疗的必要性。
