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建立预测血液透析患者心力衰竭风险的列线图。

Establishment of a nomogram that predicts the risk of heart failure in hemodialysis patients.

作者信息

Luo Jie, Rui Zhangru, He Yun, Li Hui, Yuan Yang, Li Wenhong

机构信息

YAN'AN Hospital of Kunming City, Kunming 650051, China.

出版信息

Am Heart J Plus. 2024 Dec 2;49:100487. doi: 10.1016/j.ahjo.2024.100487. eCollection 2025 Jan.

Abstract

Chronic kidney disease (CKD) is expected to become the fifth leading cause of death globally by 2040. Cardiovascular disease (CVD), particularly heart failure (HF), is a severe complication in CKD patients on hemodialysis. This study aimed to develop a nomogram to predict the risk of heart failure hospitalization in hemodialysis patients, providing a valuable tool for clinical decision-making. We retrospectively analyzed data from 196 patients at Kunming Yanan Hospital's hemodialysis center, including demographic, dialysis-related, and laboratory information. Significant HF predictors identified through univariate and multivariate logistic regression were age, diabetes, dialysis duration, left ventricular mass index (LVMI), albumin (ALB), and ejection fraction (EF). These predictors formed the basis of the nomogram, which demonstrated good discrimination (AUC = 0.728) and calibration (Hosmer-Lemeshow test,  = 0.463). Decision curve analysis confirmed the nomogram's clinical utility across various threshold probabilities. This study's findings can help clinicians identify high-risk patients, improving management strategies and potentially reducing HF-related hospitalizations in the hemodialysis population.

摘要

预计到2040年,慢性肾脏病(CKD)将成为全球第五大死因。心血管疾病(CVD),尤其是心力衰竭(HF),是接受血液透析的CKD患者的严重并发症。本研究旨在开发一种列线图,以预测血液透析患者心力衰竭住院风险,为临床决策提供有价值的工具。我们回顾性分析了昆明延安医院血液透析中心196例患者的数据,包括人口统计学、透析相关和实验室信息。通过单因素和多因素逻辑回归确定的显著HF预测因素为年龄、糖尿病、透析时间、左心室质量指数(LVMI)、白蛋白(ALB)和射血分数(EF)。这些预测因素构成了列线图的基础,该列线图显示出良好的区分度(AUC = 0.728)和校准度(Hosmer-Lemeshow检验,= 0.463)。决策曲线分析证实了列线图在各种阈值概率下的临床实用性。本研究结果可帮助临床医生识别高危患者,改善管理策略,并可能减少血液透析人群中与HF相关的住院率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85a0/11699596/2830b8416ec9/gr1.jpg

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本文引用的文献

1
Hypertension in chronic kidney disease-treatment standard 2023.
Nephrol Dial Transplant. 2023 Nov 30;38(12):2694-2703. doi: 10.1093/ndt/gfad118.
3
Prevalence of Chronic Kidney Disease in China: Results From the Sixth China Chronic Disease and Risk Factor Surveillance.
JAMA Intern Med. 2023 Apr 1;183(4):298-310. doi: 10.1001/jamainternmed.2022.6817.
5
Effects of Dapagliflozin in Patients With Kidney Disease, With and Without Heart Failure.
JACC Heart Fail. 2021 Nov;9(11):807-820. doi: 10.1016/j.jchf.2021.06.017. Epub 2021 Aug 23.
6
Kidney Function and Outcomes in Patients Hospitalized With Heart Failure.
J Am Coll Cardiol. 2021 Jul 27;78(4):330-343. doi: 10.1016/j.jacc.2021.05.002. Epub 2021 May 11.
7
KDIGO 2020 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease.
Kidney Int. 2020 Oct;98(4S):S1-S115. doi: 10.1016/j.kint.2020.06.019.
8
Management of heart failure in patients with end-stage kidney disease on maintenance dialysis: a practical guide.
Rev Cardiovasc Med. 2020 Mar 30;21(1):31-39. doi: 10.31083/j.rcm.2020.01.24.
10
Executive summary for the 2015 Annual Data Report of the China Kidney Disease Network (CK-NET).
Kidney Int. 2019 Mar;95(3):501-505. doi: 10.1016/j.kint.2018.11.011.

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