Thomas J M, Cranston D, Knox A J
Ann R Coll Surg Engl. 1985 Mar;67(2):79-82.
Forty-three patients operated upon for hyperparathyroidism over a 7-year period are reviewed with reference to modes of presentation, symptoms and symptomatic response following operation (76% of symptoms cured or improved). The patterns of presentation are discussed in relation to the increasing use of routine biochemical screening; emphasis is given to the symptoms admitted by 17 so-called 'asymptomatic' patients diagnosed in this way and to their improvement following surgery (75% of symptoms). Symptomatic improvement among a similar group of seventeen 'asymptomatic' patients undergoing operations for thyroid swellings was observed in only 9% of symptoms. In the light of such subjective improvement following parathyroidectomy, the theoretical prophylactic benefit of operation and its lack of morbidity, an aggressive surgical approach to the disease is considered justified.
回顾了43例在7年期间接受甲状旁腺功能亢进手术的患者，涉及手术前的表现方式、症状以及手术后症状的改善情况（76%的症状得到治愈或改善）。结合常规生化筛查的日益普及，讨论了临床表现模式；重点关注了17例通过这种方式诊断出的所谓“无症状”患者所承认的症状，以及他们术后症状的改善情况（75%的症状）。在一组类似的17例因甲状腺肿大接受手术的“无症状”患者中，仅9%的症状有改善。鉴于甲状旁腺切除术后有这种主观改善，手术的理论预防益处及其低发病率，认为对该疾病采取积极的手术方法是合理的。
