van der Ham Ineke J M, Claessen Michiel H G
Health, Medical, and Neuropsychology, Leiden University, Leiden, the Netherlands.
Neurocase. 2025 Apr;31(2):53-61. doi: 10.1080/13554794.2024.2442552. Epub 2025 Jan 7.
Developmental Topographical Disorientation (DTD) refers to impaired ability to create and consult mental maps in the absence of neurological abnormalities. We present the case study of I.S. to explore diagnostic opportunities for DTD. I.S. showed a very specific impairment in the ability to visualize spatial environments. Impaired performance was found for map use, map recognition and spatial working memory. The interview and observations showed I.S.'s quality of life and life choices have been severely affected by her navigation complaints, which have most likely been misdiagnosed repeatedly. We highlight the importance of awareness of DTD in clinicians and provide clinical recommendations.
发育性地形定向障碍(DTD)是指在没有神经学异常的情况下,创建和参考心理地图的能力受损。我们介绍了I.S.的案例研究,以探索DTD的诊断机会。I.S.在可视化空间环境的能力方面表现出非常特殊的损伤。在地图使用、地图识别和空间工作记忆方面发现了表现受损的情况。访谈和观察表明,I.S.的生活质量和生活选择受到其导航问题的严重影响,这些问题很可能被反复误诊。我们强调临床医生认识DTD的重要性,并提供临床建议。