Visakh T, Priya P S, Panakkal Nitika C, Banga Gunjan, Prakashini Koteshwar
Department of Medical Imaging Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Department of Radio Diagnosis and Imaging, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
J Clin Imaging Sci. 2024 Dec 30;14:50. doi: 10.25259/JCIS_153_2024. eCollection 2024.
Cardiac computed tomography (CCT) plays a key role in diagnosing congenital heart disease (CHD), emphasizing the need for specialized protocols in newborns due to CHD's complexity. The aim is to explore the relationship between peak enhancement time (PET) and various parameters during CHD assessment with CCT.
The study involved 38 CHD patients undergoing CCT, with observations made on their heart rate, respiratory rate, saturation, cardiac output, weight, height, and age. The PET for each case was determined, and Spearman's rank correlation was employed to evaluate the association between these parameters and the PET.
The median PET was 20.63 s, with a mean aortic Hounsfield unit of 512.16 ± 160.56. A moderate negative correlation was found between PET and both heart rates (r = -0.42, = 0.009) and respiratory rates (r = -0.41, = 0.01), whereas a negligible positive correlation (r = 0.19, = 0.25) was observed with SpO2. A moderate positive correlation was noted between PET and both weight (r = 0.44, = 0.005) and height (r = 0.40, = 0.01). In addition, there were significant differences in median PET across different age categories.
The findings conclude that PET during CCT is significantly associated with heart rate and respiratory rate. An increase in these rates corresponds to a notable decrease in PET. Consequently, the study recommends minimizing scan delays in CCT for patients exhibiting higher heart rates.
心脏计算机断层扫描（CCT）在先天性心脏病（CHD）诊断中起着关键作用，鉴于CHD的复杂性，新生儿需要专门的方案。目的是探讨CCT评估CHD期间峰值强化时间（PET）与各种参数之间的关系。
该研究纳入了38例接受CCT的CHD患者，观察其心率、呼吸频率、饱和度、心输出量、体重、身高和年龄。确定每个病例的PET，并采用Spearman等级相关性评估这些参数与PET之间的关联。
PET中位数为20.63秒，主动脉平均亨氏单位为512.16±160.56。发现PET与心率（r = -0.42，P = 0.009）和呼吸频率（r = -0.41，P = 0.01）均呈中度负相关，而与SpO2呈可忽略不计的正相关（r = 0.19，P = 0.25）。PET与体重（r = 0.44，P = 0.005）和身高（r = 0.40，P = 0.01）均呈中度正相关。此外，不同年龄组的PET中位数存在显著差异。
研究结果表明，CCT期间的PET与心率和呼吸频率显著相关。这些速率的增加对应于PET的显著降低。因此，该研究建议对于心率较高的患者，尽量减少CCT扫描延迟。
