具有45,X/46,XXp-/46,XX/47,XXX核型的特纳综合征患者发生多种癌症。
Multiple cancers in a Turner's syndrome with 45,X/46,XXp-/46,XX/47,XXX karyotype.
作者信息
Ochi H, Takeuchi J, Sandberg A A
出版信息
Cancer Genet Cytogenet. 1985 Apr 15;16(4):335-9. doi: 10.1016/0165-4608(85)90241-9.
PMID:3978600
Abstract
A female patient with a clinical picture of Turner's syndrome had five separate malignant tumors (three squamous cell carcinomas of the tongue, a colon cancer, and a glioblastoma multiforme). Her peripheral blood cells showed a 45,X/46,XXp-/46,XX/47,XXX mosaicism. The findings are discussed in relation to other extragonadal tumors in Turner's syndrome reported to-date.
摘要
一名具有特纳综合征临床表现的女性患者患有五种不同的恶性肿瘤（舌部的三例鳞状细胞癌、一例结肠癌和一例多形性胶质母细胞瘤）。她的外周血细胞显示出45,X/46,XXp-/46,XX/47,XXX嵌合体现象。本文结合迄今报道的特纳综合征其他性腺外肿瘤对这些发现进行了讨论。
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