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体重支持下的太极云手训练对脑卒中患者上肢运动功能的影响:一项三臂平行随机对照试验。

Effects of body weight-supported Tai Chi Yunshou training on upper limb motor function in stroke patients: A three-arm parallel randomized controlled trial.

作者信息

Zhang Liying, Yu Xiaoming, Liao Wangsheng, Wang Jiening, Lu Yan, Wang Naizhen, Huanxia Zhou

机构信息

Department of Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Department of Neurology, Fujian Provincial Governmental Hospital, Fujian, China.

出版信息

PLoS One. 2025 Jan 9;20(1):e0314025. doi: 10.1371/journal.pone.0314025. eCollection 2025.

Abstract

OBJECTIVES

To form a unique body weight support-Tai Chi Yunshou (BWS-TCY) training method, apply it to the treatment of upper limb dysfunction after stroke, and provide a new safe and effective treatment method for the clinic.

METHODS

A total of 93 subjects were recruited and randomly divided into conventional rehabilitation treatment (CRT) group, BWS-TCY group and traditional robot-assisted training (RAT) group in equal proportions. Subjects in the CRT group received 60 minutes of CRT daily. Subjects in the BWS-TCY group received 30 minutes of CRT and 30 minutes of BWS-TCY. Subjects in the RAT group received 30 minutes of CRT and 30 minutes of RAT. All interventions were conducted 5 days per week for 12 weeks. Outcome assessments included the Fugl-Meyer Upper Extremity Motor Function Assessment (FMA-UE), Wolf Motor Function Test (WMFT), absolute angular error (AAE), joint range of motion (JMA), modified Barthel Index (MBI), and stroke-related quality of life. Table (SS-QOL). Outcome measures were assessed at baseline, 4 weeks, 8 weeks, and 12 weeks later, and statistical analyzes were performed using two-way repeated measures analysis of variance.

RESULTS

After 12 weeks of intervention, significant improvements were observed in all evaluation indicators for the three groups of subjects compared to before the intervention. The upper limb motor function (FMA-UE and WMFT) and proprioception (AAE) showed time effects, time × group interaction effects, and group effects. When comparing the groups, the FMA-UE in the BWS-TCY group, as well as the WMFT and MBI, showed statistically significant differences compared to the CRT group (P<0.05), but not statistically significant compared to the RAT group (P>0.05). The AAE of the BWS-TCY group showed no statistical difference (P>0.05) when compared to the CRT group and RAT group. Furthermore, a time effect was observed on the rotation direction (P<0.05), and pairwise comparison between groups revealed that the BWS-TCY group performed better than both the CRT group and the RAT group. After 12 weeks of intervention, there were time effects and interaction effects between BWS-TCY and daily living activities (MBI) and quality of life (SS-QOL), but no group effect was observed. There was no statistical difference between the two groups in SS-QOL. However, there was a statistical difference (P<0.01) in MBI between the two groups.

CONCLUSIONS

The 12-week BWS-TCY intervention has been shown to effectively improve upper limb motor function.

TRIAL REGISTRATION

Retrospectively registered at chictr.org.cn on August 31, 2022 [ChiCTR2200063150] https://www.chictr.org.cn/showproj.html?proj=176229.

摘要

目的

构建一种独特的体重支持-太极云手(BWS-TCY)训练方法,将其应用于中风后上肢功能障碍的治疗,为临床提供一种新的安全有效的治疗方法。

方法

共招募93名受试者,随机等分为传统康复治疗(CRT)组、BWS-TCY组和传统机器人辅助训练(RAT)组。CRT组受试者每天接受60分钟的CRT。BWS-TCY组受试者接受30分钟的CRT和30分钟的BWS-TCY。RAT组受试者接受30分钟的CRT和30分钟的RAT。所有干预每周进行5天,共12周。结局评估包括Fugl-Meyer上肢运动功能评估(FMA-UE)、Wolf运动功能测试(WMFT)、绝对角度误差(AAE)、关节活动范围(JMA)、改良Barthel指数(MBI)以及中风相关生活质量量表(SS-QOL)。在基线、4周、8周和12周后评估结局指标,并使用双向重复测量方差分析进行统计分析。

结果

干预12周后,三组受试者的所有评估指标与干预前相比均有显著改善。上肢运动功能(FMA-UE和WMFT)及本体感觉(AAE)显示出时间效应、时间×组间交互效应和组间效应。组间比较时,BWS-TCY组的FMA-UE以及WMFT和MBI与CRT组相比有统计学显著差异(P<0.05),但与RAT组相比无统计学显著差异(P>0.05)。BWS-TCY组的AAE与CRT组和RAT组相比无统计学差异(P>0.05)。此外,在旋转方向上观察到时间效应(P<0.05),组间两两比较显示BWS-TCY组的表现优于CRT组和RAT组。干预12周后,BWS-TCY与日常生活活动(MBI)和生活质量(SS-QOL)之间存在时间效应和交互效应,但未观察到组间效应。两组在SS-QOL方面无统计学差异。然而,两组在MBI方面存在统计学差异(P<0.01)。

结论

为期12周的BWS-TCY干预已被证明能有效改善上肢运动功能。

试验注册

于2022年8月31日在chictr.org.cn进行回顾性注册[ChiCTR2200063150] https://www.chictr.org.cn/showproj.html?proj=176229

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