虫子能消除刺痛。

Bugs take the sting out.

作者信息

Liu Arren J, Lynch Jonathan B

机构信息

Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD, USA.

出版信息

Cell Host Microbe. 2025 Jan 8;33(1):15-16. doi: 10.1016/j.chom.2024.12.008.

DOI:10.1016/j.chom.2024.12.008

PMID:39788094

Abstract

Jiang et al. investigate the role of the microbiota in postherpetic neuralgia (PHN), a chronic pain condition resulting from varicella-zoster virus reactivation. They identify microbiome alterations in PHN patients, linking microbes and pain sensitivity. The researchers identify butyrate-producing Roseburia intestinalis as a mediator of pain sensitivity along the "gut-brain axis."

摘要

姜等人研究了微生物群在带状疱疹后神经痛（PHN）中的作用，PHN是一种由水痘-带状疱疹病毒再激活引起的慢性疼痛病症。他们确定了PHN患者的微生物组改变，将微生物与疼痛敏感性联系起来。研究人员确定产丁酸的肠道罗斯拜瑞氏菌是沿“肠-脑轴”的疼痛敏感性介质。