Do Kiet T, Hoang Duy K, Luong Quan N, Nguyen Huy G, Do An T, Ho-Pham Lan T, Nguyen Tuan V
Department of Internal Medicine, Le Van Thinh Hospital, Ho Chi Minh City, Vietnam.
Saigon Precision Medicine Research Center, Ho Chi Minh City, Vietnam.
J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13689. doi: 10.1002/jcsm.13689.
Falls and sarcopenia are significant public health issues in Vietnam. Despite muscle strength being a critical predictor for these conditions, reference data on muscle strength within the Vietnamese population are lacking.
To establish the reference ranges for muscle strength among Vietnamese individuals.
The study involved 4096 individuals, including 1419 men and 2677 women aged 18 years and above, from the Vietnam Osteoporosis Study. Muscle strength was assessed using a Baseline hand dynamometer for handgrip strength and a Back-Leg-Chest dynamometer for leg strength. We calculated mean values, standard deviations, interquartile ranges, and peak muscle strength (pMS) for both handgrip and leg strength across various ages. Reference curves were created with the Generalised Additive Model for Location Scale and Shape, and polynomial regression models were employed to analyse the relationship between muscle strength and age.
Advancing age was significantly associated with lower muscle strength. Peak muscle strength typically occurred between ages 30 and 40, with earlier peaks in women, especially in leg strength. Men consistently showed higher muscle strength than women, with variations depending on the measurement site. Specifically, average handgrip strength was 36.4 kg ± 8.4 (mean ± SD) for men and 23.2 kg ± 6.0 for women (p < 0.001). Leg strength averaged 63.9 kg ± 27.2 for men and 29.5 kg ± 13.9 for women (p < 0.001). Additionally, we produced a percentile chart illustrating muscle weakness ranges based on the 25th percentile of muscle strength and the appendicular skeletal muscle mass index (ASMI) for the Vietnamese population.
These data provide reference ranges for evaluating muscle strength in the Vietnamese population, offering crucial insights for identifying individuals at risk of falls or sarcopenia in clinical settings.
跌倒和肌肉减少症是越南重要的公共卫生问题。尽管肌肉力量是这些情况的关键预测指标,但越南人群中肌肉力量的参考数据却很缺乏。
建立越南个体肌肉力量的参考范围。
该研究纳入了4096名18岁及以上的个体,其中包括1419名男性和2677名女性,数据来自越南骨质疏松症研究。使用基线握力计评估握力,使用背腿胸测力计评估腿部力量。我们计算了不同年龄段握力和腿部力量的平均值、标准差、四分位数间距和峰值肌肉力量(pMS)。利用位置尺度和形状的广义相加模型创建参考曲线,并采用多项式回归模型分析肌肉力量与年龄之间的关系。
年龄增长与肌肉力量降低显著相关。峰值肌肉力量通常出现在30至40岁之间,女性出现峰值的时间更早,尤其是腿部力量。男性的肌肉力量始终高于女性,且因测量部位而异。具体而言,男性平均握力为36.4千克±8.4(均值±标准差),女性为23.2千克±6.0(p<0.001)。男性腿部力量平均为63.9千克±27.2,女性为29.5千克±13.9(p<0.001)。此外,我们还制作了一个百分位数图表,根据越南人群肌肉力量的第25百分位数和附属骨骼肌质量指数(ASMI)说明了肌肉无力范围。
这些数据为评估越南人群的肌肉力量提供了参考范围,为在临床环境中识别有跌倒或肌肉减少症风险的个体提供了关键见解。