Ter Wei Chua, Musa Muharliza, Mohamad Rosilah, Mohd Khialdin Safinaz
Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, MYS.
Department of Ophthalmology, Hospital University Kebangsaan Malaysia, Kuala Lumpur, MYS.
Cureus. 2024 Dec 9;16(12):e75414. doi: 10.7759/cureus.75414. eCollection 2024 Dec.
We report a rare case of a missed intracavernous internal carotid artery dissecting aneurysm occurring as a complication of the base of skull fracture with severe brain injury causing acute cavernous sinus syndrome with permanent vision loss. A 31-year-old Myanmar lady had an alleged motor vehicle accident and suffered severe traumatic brain injury with multiple intracranial bleeds, multiple facial bone and base of skull fractures, and limb fractures. At one week post-trauma, she had severe right eye proptosis with vision loss, ophthalmoplegia, chemosis, and high intraocular pressure. She was suspected clinically to have a traumatic cavernous carotid fistula and a lateral canthotomy and cantholysis was performed. The patient was scheduled for an embolization of the fistula but during cerebral digital subtraction angiography, a dissecting aneurysm instead was noted at the right internal carotid artery at the cavernous segment. A cerebral computed tomography angiography and venography showed right cavernous sinus and right superior ophthalmic vein thrombosis. The patient was started on antiplatelet agents and underwent successful stenting-assisted coiling of the aneurysm, and her right eye proptosis gradually resolved. While awaiting definitive treatment of the aneurysm, the patient had severe exposure keratopathy and despite intensive hydration and antimicrobial treatment, it later developed into a fungal corneal ulcer. A temporary tarsorrhaphy was done and the ulcer gradually healed into a significant corneal scar and the final visual acuity of her right eye was no light perception. The underlying cause of cavernous sinus syndrome is diverse and unique. A thorough assessment and appropriate neuroimaging should be performed to arrive at the proper diagnosis in a timely manner. This is in order to prevent delays in the definitive treatment and irreversible ocular morbidity.
我们报告了一例罕见的漏诊海绵窦段颈内动脉夹层动脉瘤,它是颅骨骨折合并严重脑损伤的并发症,导致急性海绵窦综合征并造成永久性视力丧失。一名31岁的缅甸女性据称遭遇机动车事故,患有严重的创伤性脑损伤,伴有多处颅内出血、多根面骨和颅骨骨折以及四肢骨折。创伤后一周,她出现严重的右眼突出伴视力丧失、眼球运动麻痹、结膜水肿和高眼压。临床怀疑她患有外伤性海绵窦瘘,并进行了外眦切开术和眦部松解术。患者原计划进行瘘管栓塞,但在脑数字减影血管造影时,发现右侧海绵窦段颈内动脉有一个夹层动脉瘤。脑部计算机断层扫描血管造影和静脉造影显示右侧海绵窦和右侧眼上静脉血栓形成。患者开始使用抗血小板药物,并成功接受了动脉瘤支架辅助弹簧圈栓塞术,右眼突出逐渐消退。在等待动脉瘤的确定性治疗期间,患者出现严重的暴露性角膜病变,尽管进行了大量补液和抗菌治疗,但后来发展为真菌性角膜溃疡。进行了临时性睑裂缝合术,溃疡逐渐愈合形成明显的角膜瘢痕,右眼最终视力为无光感。海绵窦综合征的潜在病因多样且独特。应进行全面评估和适当的神经影像学检查,以便及时做出正确诊断。这是为了防止确定性治疗的延误和不可逆转的眼部疾病。