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意外危及生命的一餐:台湾地区的米酵菌酸污染事件

Unexpectedly life-threatening meal: Contamination by Bongkrekic acid in Taiwan.

作者信息

Yu Ching-Hsiang, Liao En-Chih, Su Yu-Jang

机构信息

Department of Emergency Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.

Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; Institute of Biomedical Sciences, MacKay Medical College, New Taipei City, Taiwan.

出版信息

Taiwan J Obstet Gynecol. 2025 Jan;64(1):142-145. doi: 10.1016/j.tjog.2024.10.003.

Abstract

OBJECTIVE

Bongkrekic acid (BKA) is a life-threatening toxin linked to foodborne illnesses. Herein, we report two fatalities among 33 patients who ingested BKA in March 2024, East Taipei, Taiwan.

CASE REPORT

Our first case involved a 40-year-old female who presented with nausea, vomiting, and diarrhea after consuming wet rice noodles. On examination, refractory hypotension, jaundice, diffuse abdominal pain, high levels of liver enzymes, metabolic acidosis, coagulopathy, and acute hepatic failure were present. Dialysis, continuous venovenous hemofiltration, and plasma exchange were performed; however, the patient experienced liver failure and died of multi-organ failure, severe sepsis, and coagulopathy on day 39. The second case, a 39-year-old man, was found unconscious and experiencing cardiac arrest. He eventually died after 30 min of cardiopulmonary resuscitation following admission to the intensive care unit.

CONCLUSION

Strengthening food safety regulations by enhancing inspection of food production, storage, and preparation facilities should be implemented to prevent BKA poisoning-related fatalities.

摘要

目的

庞克雷酸(BKA)是一种与食源性疾病相关的致命毒素。在此,我们报告2024年3月在台湾台北东部摄入BKA的33例患者中有2例死亡。

病例报告

我们的首例病例是一名40岁女性,食用湿米粉后出现恶心、呕吐和腹泻。检查发现有难治性低血压、黄疸、弥漫性腹痛、肝酶水平升高、代谢性酸中毒、凝血障碍和急性肝衰竭。进行了透析、持续静脉-静脉血液滤过和血浆置换;然而,患者出现肝衰竭,于第39天死于多器官功能衰竭、严重脓毒症和凝血障碍。第二例病例是一名39岁男性,被发现昏迷并发生心脏骤停。他在重症监护病房入院后经过30分钟的心肺复苏最终死亡。

结论

应通过加强对食品生产、储存和制备设施的检查来强化食品安全法规,以预防与BKA中毒相关的死亡。

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