一次性负压伤口治疗(sNPWT)与标准敷料在同一患者双侧组织扩张器至植入物置换过程中的应用比较。
Comparison of Single-Use Negative-Pressure Wound Therapy (sNPWT) and Standard Dressings Applied to the Same Patient During Bilateral Tissue Expander-to-Implant Exchanges.
作者信息
Molska Maja, Wojciech Magdalena, Murawa Dawid
机构信息
Clinical Department of General and Oncological Surgery, University Hospital in Zielona Góra, 65-046 Zielona Góra, Poland.
Department of Surgery and Oncology, Collegium Medicum, University of Zielona Góra, 65-046 Zielona Góra, Poland.
出版信息
Cancers (Basel). 2024 Dec 24;17(1):3. doi: 10.3390/cancers17010003.
BACKGROUND
Breast cancer is the most common cancer among women. The number of cases is increasing among young women, and consequently, breast reconstructions are performed more often. Postoperative complications, wound healing, and the quality of scars influence the final cosmetic outcomes. The aim of the study was to investigate the effect of using a negative-pressure therapy compared to a standard dressing on two postoperative wounds in the same woman, after bilateral tissue expander replacement surgery-when identical healing conditions occur.
METHODS
This study includes a single-center evaluation of the application of two different dressings during bilateral exchanges of tissue expanders with breast implants. The study included 22 patients with a history of breast cancer after bilateral mastectomy with two-stage reconstruction. During the second stage, a sNPWT was applied to one breast and a standard dressing to the other.
RESULTS
A statistically significant difference in skin elasticity in favor of sNPWT was visible after 7 days, while the greatest difference was visible in the evaluation after 6 months (mean of 0.806 vs. 0.607). A difference in temperature measurements was shown 7 days after the procedure. However, after 30 days, these measurements were similar. There was also a reduced incidence of postoperative complications as well as seroma accumulation in the breasts with negative pressure.
CONCLUSIONS
The results indicate faster healing, better scar quality, and improved skin elasticity in breasts with sNPWT compared to the standard dressing. The number of postoperative complications were also reduced, which is especially important in high-risk patients.
背景
乳腺癌是女性中最常见的癌症。年轻女性中的病例数量正在增加,因此,乳房重建手术的实施更为频繁。术后并发症、伤口愈合以及疤痕质量会影响最终的美容效果。本研究的目的是在双侧组织扩张器置换手术后,当相同的愈合条件出现时,比较在同一女性的两个术后伤口上使用负压疗法与标准敷料的效果。
方法
本研究包括对在双侧乳房植入物组织扩张器置换过程中应用两种不同敷料的单中心评估。该研究纳入了22例双侧乳房切除术后进行两阶段重建的乳腺癌患者。在第二阶段,一侧乳房应用sNPWT,另一侧应用标准敷料。
结果
7天后可见皮肤弹性在有利于sNPWT方面有统计学显著差异,而在6个月后的评估中差异最大(平均值分别为0.806和0.607)。术后7天显示出温度测量的差异。然而,30天后,这些测量结果相似。负压治疗的乳房术后并发症发生率以及血清肿积聚也有所降低。
结论
结果表明,与标准敷料相比,sNPWT治疗的乳房愈合更快、疤痕质量更好、皮肤弹性改善。术后并发症数量也减少了,这在高危患者中尤为重要。
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