Yu Xinlei, Elazab Ahmed, Ge Ruiquan, Zhu Jichao, Zhang Lingyan, Jia Gangyong, Wu Qing, Wan Xiang, Li Lihua, Wang Changmiao
School of Computer Science, Hangzhou Dianzi University, Hangzhou, 310018, China.
School of Biomedical Engineering, Shenzhen University, Shenzhen, 518037, China.
Neural Netw. 2025 Apr;184:107096. doi: 10.1016/j.neunet.2024.107096. Epub 2025 Jan 6.
Accurately predicting intracerebral hemorrhage (ICH) prognosis is a critical and indispensable step in the clinical management of patients post-ICH. Recently, integrating artificial intelligence, particularly deep learning, has significantly enhanced prediction accuracy and alleviated neurosurgeons from the burden of manual prognosis assessment. However, uni-modal methods have shown suboptimal performance due to the intricate pathophysiology of the ICH. On the other hand, existing cross-modal approaches that incorporate tabular data have often failed to effectively extract complementary information and cross-modal features between modalities, thereby limiting their prognostic capabilities. This study introduces a novel cross-modal network, ICH-PRNet, designed to predict ICH prognosis outcomes. Specifically, we propose a joint-attention interaction encoder that effectively integrates computed tomography images and clinical texts within a unified representational space. Additionally, we define a multi-loss function comprising three components to comprehensively optimize cross-modal fusion capabilities. To balance the training process, we employ a self-adaptive dynamic prioritization algorithm that adjusts the weights of each component, accordingly. Our model, through these innovative designs, establishes robust semantic connections between modalities and uncovers rich, complementary cross-modal information, thereby achieving superior prediction results. Extensive experimental results and comparisons with state-of-the-art methods on both in-house and publicly available datasets unequivocally demonstrate the superiority and efficacy of the proposed method. Our code is at https://github.com/YU-deep/ICH-PRNet.git.