Gavillero Martín A, Juliá Roca M, Serra-Guillén I, Rodríguez-Hernández A, Manrique-Silva E, López-Sundh A E, Nagore E
School of Medicine, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain.
Escuela de Doctorado, Universidad Católica de Valencia San Vicente Martir, Valencia, Spain.
Actas Dermosifiliogr. 2025 May;116(5):455-461. doi: 10.1016/j.ad.2024.09.027. Epub 2025 Jan 10.
Biosynthetic porcine type I collagen dressing is useful to close ulcers and secondary intention healing of surgical cancer wounds.
To identify factors associated with the healing time of such wounds.
We conducted a retrospective observational study of patients on oncological dermatological surgery in a cancer center. Healing time was studied based on age, sex, personal history of comorbidities, usual medication, anatomical location, type of surgery performed and size of the defect. Statistical analysis was performed using the ANOVA test and logistic regression.
A total of 306 patients were included with a median age of 73 years (62.4%, men). The statistically significantly characteristics associated with a healing time≤66 days were location-auricle, nose, inner canthus, hand, retroauricular region and nail bed-use of the Mohs technique and defect sizes≤5.28cm.
This is a retrospective study from a single center.
The use of biosynthetic porcine type I collagen dressings for the definitive closure of dermatological surgical cancer wounds seems particularly suitable for small defects of the inner canthus of the eye, hand, auricle, nose, forehead, retroauricular region, and nail bed.
生物合成猪I型胶原蛋白敷料有助于闭合溃疡以及外科癌症伤口的二期愈合。
确定与此类伤口愈合时间相关的因素。
我们在一家癌症中心对接受肿瘤皮肤科手术的患者进行了一项回顾性观察研究。根据年龄、性别、合并症个人史、常用药物、解剖位置、所进行的手术类型以及缺损大小来研究愈合时间。使用方差分析测试和逻辑回归进行统计分析。
共纳入306例患者，中位年龄为73岁（男性占62.4%）。与愈合时间≤66天相关的具有统计学意义的特征为位置——耳廓、鼻子、内眦、手部、耳后区域和甲床，使用莫氏技术以及缺损大小≤5.28厘米。
这是一项来自单一中心的回顾性研究。
使用生物合成猪I型胶原蛋白敷料来最终闭合皮肤外科癌症伤口似乎特别适用于眼内眦、手部、耳廓、鼻子、前额、耳后区域和甲床的小缺损。
