Al Hussaini Hussam Al Deen, Alatawi Ebtesam Saleem Eid, Shabani Jenan Ali J, Edhrabooh Maryam Isa Hasan, Alhawaj Shaikha Abduljalil Abdulla, Almahfoodh Maryam Sayed, Alsamiri Halimah Yaseen, AlMaatoug Ali Reda, Hayderali Maryam Ismail M, Almousa Mohammed Ramzi
Obstetrics and Gynecology, Maternity and Children Hospital, Tabuk, SAU.
Obstetrics and Gynecology, Maternity And Children Hospital, Tabuk, SAU.
Cureus. 2024 Dec 12;16(12):e75590. doi: 10.7759/cureus.75590. eCollection 2024 Dec.
Endometriosis is a chronic, inflammatory disease characterized by the presence of endometrial-like tissue outside the uterus, affecting women of reproductive age. It is linked with debilitating pain, infertility, and a notable impact on the patient's quality of life. This review aims to highlight the effectiveness of hormonal therapy, surgical procedures, and complementary therapies in managing endometriosis-related pain, providing a comprehensive overview of current treatment options and their implications for clinical practice. The literature reveals that hormonal therapies, including combined oral contraceptives, progestins, and gonadotropin-releasing hormone (GnRH) agonists, are frequently used to manage endometriosis-related pain by suppressing ovarian function and reducing menstrual flow. Surgical interventions, such as laparoscopy and hysterectomy, offer pain relief by removing endometrial lesions but carry risks of recurrence and complications. Complementary therapies, including acupuncture, dietary modifications, and physical therapy, are increasingly recognized for their potential to minimize pain and improve patients' quality of life, though evidence of their effectiveness varies. The review highlights the need for personalized treatment plans that consider patient preferences, symptom severity, and reproductive goals. Future research should concentrate on the long-term outcomes of different therapies, the advancement of non-invasive diagnostic methods, and the identification of biomarkers for tailored treatment approaches. Clinicians are encouraged to adopt an interdisciplinary approach to endometriosis management, integrating medical, surgical, and complementary therapies to optimize patient outcomes.
子宫内膜异位症是一种慢性炎症性疾病，其特征是子宫外存在类似子宫内膜的组织，影响育龄女性。它与使人衰弱的疼痛、不孕以及对患者生活质量的显著影响有关。本综述旨在强调激素疗法、手术程序和辅助疗法在管理子宫内膜异位症相关疼痛方面的有效性，全面概述当前的治疗选择及其对临床实践的影响。文献表明，激素疗法，包括复方口服避孕药、孕激素和促性腺激素释放激素（GnRH）激动剂，常用于通过抑制卵巢功能和减少月经流量来管理子宫内膜异位症相关疼痛。手术干预，如腹腔镜检查和子宫切除术，通过切除子宫内膜病变来缓解疼痛，但存在复发和并发症的风险。辅助疗法，包括针灸、饮食调整和物理治疗，因其减轻疼痛和改善患者生活质量的潜力而越来越受到认可，尽管其有效性的证据各不相同。该综述强调需要制定个性化的治疗方案，考虑患者的偏好、症状严重程度和生殖目标。未来的研究应集中在不同疗法的长期结果、非侵入性诊断方法的进展以及确定个性化治疗方法的生物标志物上。鼓励临床医生采用跨学科方法管理子宫内膜异位症，整合医学、手术和辅助疗法以优化患者的治疗效果。
