Metry Arsany, Manzoor Nauman, Elkilany Ahmed, Wattage Kanishka, Sain Arnab, Hussain Fahad, Khilla Kerollos, Sohail Zain, Abdulkarim Ali
Trauma and Orthopaedics, University Hospitals Sussex National Health Service (NHS) Foundation Trust, Sussex, GBR.
General Surgery, University Hospitals Sussex National Health Service (NHS) Foundation Trust, Sussex, GBR.
Cureus. 2024 Dec 12;16(12):e75594. doi: 10.7759/cureus.75594. eCollection 2024 Dec.
The aim of the study is to identify the potential risk factors for postoperative AKI in hip fracture patients.
Using our local neck of femur (NOF) registration data, patient details were selected using inclusion and exclusion criteria. Electronic records of patients were assessed retrospectively, including blood results, radiological investigations, clinical documentation, and drug charts. The time period was from the start of January 2022 to the end of June 2022.
All patients > 50 years old with NOF fractures underwent operative management from January 2022 to June 2022.
Two hundred and fifty patients underwent hip fracture surgery at our hospital in 6 months (January 2022-June 2022) (Cemented procedures were 133 [53%], while fixation procedures were 117 [47%]). Female patients were 174 (70%), and male patients were 76. The average age was 83.4 years, and the number of operations done over the weekend (Friday-Sunday) = 123 (49%). The incidence of postoperative AKI was 56 (22.4%). Forty-five of the fifty-six cases were stage one (80.4%), while seven cases (12.5%) were stage 2. The studied risk factors for postoperative AKI were cemented procedures (61% of postoperative AKI incidence), female gender (66%), time from admission to operation (>24 hours = 33%), day of operation (operations done Friday/Saturday/Sunday = 55%), and postoperative antibiotics (71%).
We need strategies to reduce the incidence of postoperative AKI, like AKI alert on laboratory results, IV fluid prescription preoperatively since the arrival of patients to the ED, avoiding/stopping nephrotoxic medications on admission, regular review of postoperative renal function tests and fluid balance, especially in high-risk patients, increase nursing staff and junior doctors on wards over weekends, and we need to review our policy of giving postoperative IV antibiotics.
本研究的目的是确定髋部骨折患者术后急性肾损伤(AKI)的潜在危险因素。
利用我们当地股骨颈(NOF)登记数据,根据纳入和排除标准选择患者详细信息。对患者的电子记录进行回顾性评估,包括血液检查结果、放射学检查、临床记录和药物图表。时间段为2022年1月开始至2022年6月结束。
2022年1月至2022年6月期间,所有年龄大于50岁的NOF骨折患者均接受了手术治疗。
2022年1月至2022年6月的6个月内,我院有250例患者接受了髋部骨折手术(骨水泥固定手术133例[53%],内固定手术117例[47%])。女性患者174例(70%),男性患者76例。平均年龄为83.4岁,周末(周五至周日)进行的手术例数为123例(49%)。术后AKI的发生率为56例(22.4%)。56例中的45例为1期(80.4%),7例(12.5%)为2期。研究的术后AKI危险因素包括骨水泥固定手术(占术后AKI发生率的61%)、女性(66%)、入院至手术时间(>24小时=33%)、手术日(周五/周六/周日进行的手术=55%)以及术后使用抗生素(71%)。
我们需要采取策略来降低术后AKI的发生率,如对实验室结果设置AKI警报、患者到达急诊科后术前静脉输液处方、入院时避免/停用肾毒性药物、定期复查术后肾功能检查和液体平衡,尤其是高危患者,周末增加病房护理人员和低年资医生,并且我们需要审查术后静脉使用抗生素的政策。