Ulcerative and Cytomegalovirus Colitis Associated with Fournier's Gangrene: A Case Report.

Fournier gangrene is a rare but severe complication of ulcerative colitis, characterized by necrotizing fasciitis affecting the genital and perineal regions. We present a case of a 53-year-old man with a history of ulcerative colitis and cytomegalovirus (CMV) colitis who developed Fournier gangrene, an exceptionally uncommon occurrence in this patient population. The patient initially presented with intense pain, swelling, and skin discoloration in the genital area, accompanied by systemic symptoms, including fever. Prompt recognition and intervention are critical due to the aggressive nature of Fournier gangrene, which often results in significant morbidity and mortality. This case underscores the importance of vigilance for unusual presentations of necrotizing infections in patients with inflammatory bowel disease (IBD), particularly those with complicating factors such as immunosuppression and concurrent infections.