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Efficacy of Intraoperative Intra-Articular Morphine on Post-Operative Pain and Opioid Consumption Following Hip Arthroscopy.

作者信息

McCulley Steele, Lapierre Jace, Delgado-Arellanes Irving, Rund Joseph, Seffker Courtney, An Qiang, Westermann Robert W

机构信息

Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

出版信息

Iowa Orthop J. 2024;44(2):112-116.


DOI:
PMID:39811176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11726484/
Abstract

BACKGROUND: The use of intraoperative intra-articular morphine has been suggested to lower postoperative pain scores and opioid use. We sought to evaluate the effectiveness of intra-articular morphine with 0.75% ropivacaine when compared to the use of ropivacaine alone. Our study's purpose was to determine the efficacy of intra-articular morphine on pain control, opioid consumption, and discharge times in the immediate post-operative period. METHODS: We retrospectively reviewed the charts of 100 patients who underwent hip arthroscopy with repair for femoroacetabular impingement (FAI) between 2021 to 2023. 50 patients who received 5 mg of intra-articular morphine injections intraoperatively were identified, and 50 who did not. Patients undergoing hip arthroscopy without repair, revision surgery, or combined hip arthroscopy and femoral osteotomy or periacetabular osteotomy were excluded. Demographics including age, sex, race, ethnicity, BMI, and tobacco use were recorded. Procedural factors included total operative time, traction time, and time to discharge. Pain scores were assessed using the Visual Analog Scale (VAS), and the initial Post-Anesthesia Care Unit (PACU) and final VAS score prior to discharge were recorded. Total acute opioid use was recorded using morphine milligram equivalents (MME) during post-operation to discharge. We used the Wilcoxon rank sum test and chi-square statistics on continuous and categorical variables, respectively. Statistically significant level was set as p<0.05. RESULTS: No significant differences were found between demographics, operative time, traction time, or discharge time. The median age of patients in the non-morphine group was 29 (48% M, 52% F) and 24.5 (34% M, 66% F) in the morphine group. Differences between the morphine and non-morphine group in postoperative VAS scores were insignificant, with the mean initial PACU VAS scores (4.6 ± 3.0 vs 5.5 ± 3.0) and mean final PACU VAS scores (3.5 ± 1.9 vs 3.7 ± 1.4) respectively. Postoperative MME consumption difference was also insignificant (17.1 ± 7.4 vs 17.9 ± 7.3). CONCLUSION: Intraoperative intra-articular morphine injection with ropivacaine does not provide a significant reduction in acute postoperative pain scores or opioid use when compared to ropivacaine use alone. Further investigation into the efficacy of intra-articular morphine is warranted. .

摘要

相似文献

[1]
Efficacy of Intraoperative Intra-Articular Morphine on Post-Operative Pain and Opioid Consumption Following Hip Arthroscopy.

Iowa Orthop J. 2024

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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本文引用的文献

[1]
In vitro chondrotoxicity of bupivacaine, levobupivacaine and ropivacaine and their effects on caspase activity in cultured canine articular chondrocytes.

J Vet Med Sci. 2023-4-22

[2]
Multimodal Pain Management in Orthopedic Surgery.

J Clin Med. 2022-10-28

[3]
Comprehensive Analysis of Opioid Use After Common Elective Outpatient Orthopaedic Surgeries.

J Am Acad Orthop Surg Glob Res Rev. 2022-4-12

[4]
Periarticular Local Infiltrative Anesthesia and Regional Adductor Canal Block Provide Equivalent Pain Relief After Anterior Cruciate Ligament Reconstruction.

Arthroscopy. 2022-4

[5]
Updates on Multimodal Analgesia for Orthopedic Surgery.

Anesthesiol Clin. 2018-9

[6]
Pain Management After Hip Arthroscopy: Systematic Review of Randomized Controlled Trials and Cohort Studies.

Am J Sports Med. 2017-10-13

[7]
Sustained Prescription Opioid Use Among Previously Opioid-Naive Patients Insured Through TRICARE (2006-2014).

JAMA Surg. 2017-12-1

[8]
New Persistent Opioid Use After Minor and Major Surgical Procedures in US Adults.

JAMA Surg. 2017-6-21

[9]
Efficacy of Surgical-Site, Multimodal Drug Injection Following Operative Management of Femoral Fractures: A Randomized Controlled Trial.

J Bone Joint Surg Am. 2017-3-15

[10]
Single-dose local anesthetics exhibit a type-, dose-, and time-dependent chondrotoxic effect on chondrocytes and cartilage: a systematic review of the current literature.

Knee Surg Sports Traumatol Arthrosc. 2017-3-13

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