Travi B L, Eberhard M L, Lowrie R C
J Parasitol. 1985 Feb;71(1):17-9.
Infective larvae of Dipetalonema gracile, which had developed in Culicoides hollensis, were inoculated into 4 laboratory-born squirrel monkeys, Saimiri sciureus. Weekly blood sampling revealed the mean prepatent period to be 297 days. All 4 monkeys developed patent infections in which peak microfilaremias were reached 13 to 18 wk after patency. Two laparotomies, performed at 27 and 64 wk, were conducted to evaluate pathological involvement and, at that later time, to recover adult parasites. Slight capsular fibrosis was observed on the spleen of 2 of the animals but fibrous adhesions were absent. Microfilaremias in the 4 monkeys ranged from 15 to 250 mf/20 mm3 of blood and the number of adult parasites recovered varied from 7 to 13. However, the level of microfilaremia did not correlate directly to the number of adult parasites recovered.
在霍氏库蠓体内发育的细尾双瓣线虫感染性幼虫被接种到4只实验室出生的松鼠猴（松鼠猴属）体内。每周采血显示平均潜伏期为297天。所有4只猴子都发生了显性感染，显性感染后13至18周达到微丝蚴血症高峰。在第27周和第64周进行了两次剖腹手术，以评估病理受累情况，并在较晚时间回收成虫寄生虫。在2只动物的脾脏上观察到轻微的包膜纤维化，但没有纤维粘连。4只猴子的微丝蚴血症范围为每20立方毫米血液中有15至250条微丝蚴，回收得到的成虫寄生虫数量从7条到13条不等。然而，微丝蚴血症水平与回收得到的成虫寄生虫数量没有直接相关性。
