[组织形态学定义的肾细胞癌2025：当前世界卫生组织分类及未来新兴亚型]
[Histomorphologically defined renal cell carcinomas 2025 : Current WHO classification and emerging future subtypes].
作者信息
Stöhr C, Fiegl A, Bercebal C, Agaimy A, Hartmann A
机构信息
Institut für Pathologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Krankenhausstraße 8-10, 91054, Erlangen, Deutschland.
Comprehensive Cancer Center EMN, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Deutschland.
出版信息
Pathologie (Heidelb). 2025 Feb;46(1):13-20. doi: 10.1007/s00292-024-01406-6. Epub 2025 Jan 16.
BACKGROUND
The latest edition of the WHO classification of urinary and male genital tumours was published in 2022. The revision was based on the newest scientific literature. This article summarizes the updated recommendations regarding the classification of histomorphologically defined tumours.
RESULTS AND CONCLUSIONS
The current edition of the WHO classification made some adjustments on the classification of histomorphologically defined tumour types. Papillary renal cell carcinoma is no longer categorized into two subtypes. Also, the new classification recognized the benign nature of clear cell papillary tumours, which are no longer regarded as carcinomas. Finally, several emerging renal tumours were introduced.
背景
世界卫生组织（WHO）泌尿及男性生殖系统肿瘤的最新分类于2022年发布。此次修订基于最新的科学文献。本文总结了关于组织形态学定义肿瘤分类的更新建议。
结果与结论
WHO分类的当前版本对组织形态学定义的肿瘤类型分类进行了一些调整。乳头状肾细胞癌不再分为两个亚型。此外，新分类认可了透明细胞乳头状肿瘤的良性性质，这类肿瘤不再被视为癌。最后，引入了几种新出现的肾肿瘤。
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