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对使用甲基苯丙胺者期望的戒断和非戒断康复结果的探索。

An exploration of desired abstinent and non-abstinent recovery outcomes among people who use methamphetamine.

作者信息

Elswick Alex, Fallin-Bennett Amanda, Roper Karen L, Batty Evan, McLouth Christopher J, Stoops William, Surratt Hilary L, Oser Carrie B

机构信息

University of Kentucky, Lexington, USA.

Voices of Hope, Lexington, USA.

出版信息

Harm Reduct J. 2025 Jan 15;22(1):7. doi: 10.1186/s12954-025-01155-6.

Abstract

BACKGROUND

In the United States, complete abstinence persists as the standard for demonstrating recovery success from substance use disorders (SUDs), apart from alcohol use disorder (AUD). Although the FDA has recently indicated openness for non-abstinence outcomes as treatment targets, the traditional benchmark of complete abstinence for new medications to treat SUDs remains a hurdle and overshadows other non-abstinent outcomes desired by people with SUDs (e.g., improved sleep, employment, family reunification). This study sought to expand the definition of recovery to include non-abstinent pathways by exploring non-abstinence-based outcomes desired by people who use methamphetamine (PWUM).

METHODS

Participants (n = 100) were recruited from existing National Institute on Drug Abuse (NIDA) projects including a treatment-seeking sample of people recently released from prison (all of whom endorsed recent methamphetamine use) and a sample of people using syringe service programs. In a convergent survey design, participants responded to closed-ended questions regarding recovery outcomes, followed by open-ended items to gain a better understanding of PWUM and their conception of recovery. The importance of non-abstinent outcomes was measured in five categories (substance use, physical health, cognitive functioning, mental health, and financial/social/relationships).

RESULTS

Participants were primarily White (88%), male (67%), and an average age of 40. Approximately two-thirds of participants agreed that people need to stop all mood- or mind-altering substances to be in recovery (64%). Nevertheless, participants indicated a variety of desired non-abstinent recovery outcomes, both substance-related (e.g. reductions in methamphetamine use) and non-substance-related (e.g. improved economic stability). Specific non-abstinent outcomes endorsed as "absolutely essential" by PWUM included: preventing legal trouble (92%), employment stability (82%), improved quality of life (80%), housing stability (78%), improved coping skills (78%), improved relationships (75%), economic/income stability (74%), ability to think clearly (73%), less impulsivity (73%), less depression (71%), less stress (70%), improved hopefulness (70%), and improved sleep (70%). Open-ended responses emphasized employment stability, economic/income stability, improved coping skills, improved relationships, as well as improved energy, appetite, and sleep.

CONCLUSION

Our findings indicate the importance of non-abstinent recovery outcomes among PWUM, suggesting high acceptability of non-abstinent recovery targets by people with lived experience. Further, the essential importance of non-abstinent outcomes, especially in the financial/social/relationship and mental health domains, were highlighted, providing novel targets for delivering SUD treatment/recovery.

摘要

背景

在美国,除酒精使用障碍(AUD)外,完全戒除仍然是证明物质使用障碍(SUDs)康复成功的标准。尽管美国食品药品监督管理局(FDA)最近表示愿意将非戒除结果作为治疗目标,但新的治疗SUDs药物的传统完全戒除基准仍然是一个障碍,并且掩盖了SUDs患者所期望的其他非戒除结果(例如,改善睡眠、就业、家庭团聚)。本研究旨在通过探索使用甲基苯丙胺者(PWUM)所期望的基于非戒除的结果,来扩大康复的定义,将非戒除途径纳入其中。

方法

参与者(n = 100)从现有的美国国立药物滥用研究所(NIDA)项目中招募,包括一个寻求治疗的刚从监狱释放的样本(所有参与者都认可近期使用过甲基苯丙胺)和一个使用注射器服务项目的样本。在一项聚合调查设计中,参与者回答了关于康复结果的封闭式问题,随后是开放式问题,以更好地了解PWUM及其对康复的概念。非戒除结果的重要性在五个类别中进行衡量(物质使用、身体健康、认知功能、心理健康以及财务/社会/人际关系)。

结果

参与者主要为白人(88%),男性(67%),平均年龄40岁。大约三分之二的参与者同意人们需要停止所有改变情绪或思维的物质才能康复(64%)。然而,参与者指出了各种期望的非戒除康复结果,包括与物质相关的(例如甲基苯丙胺使用量减少)和与非物质相关的(例如经济稳定性提高)。PWUM认为“绝对必要”的具体非戒除结果包括:避免法律麻烦(92%)、就业稳定(82%)、生活质量改善(80%)、住房稳定(78%)、应对技能提高(78%)、人际关系改善(75%)、经济/收入稳定(74%)、思维清晰的能力(73%)、冲动性降低(73%)、抑郁减轻(71%)、压力减轻(70%)、希望感增强(70%)以及睡眠改善(70%)。开放式回答强调了就业稳定、经济/收入稳定、应对技能提高、人际关系改善,以及精力、食欲和睡眠的改善。

结论

我们的研究结果表明非戒除康复结果在PWUM中的重要性,表明有实际经验的人对非戒除康复目标具有较高的接受度。此外,突出了非戒除结果的至关重要性,特别是在财务/社会/人际关系和心理健康领域,为提供SUD治疗/康复提供了新的目标。

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