Akhavan-Sigari Amirhossein, Park David J, Harary Paul M, Chivakula Maya, Theodros Debebe, Bharani Krishna L, Hori Yusuke S, Persad Amit R L, Lam Fred C, Emrich Sara C, Ustrzynski Louisa, Tayag Armine, Chang Steven D
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Department of Pathology, Stanford University School of Medicine, Stanford, California.
J Neurosurg Case Lessons. 2025 Jan 20;9(3). doi: 10.3171/CASE24551.
The co-occurrence of Rathke cleft cysts (RCCs) and meningiomas in the sellar and parasellar regions represents an exceedingly rare clinical entity. Achieving maximal resection through a single operative approach while minimizing adverse events is challenging, often necessitating multiple surgical approaches, as suggested by previous reports.
The authors report the case of a 49-year-old female with a history of kidney transplant who presented with headaches and was diagnosed with coexisting RCC and meningioma in the sellar and planum sphenoidale regions, respectively. Given the prolonged, refractory nature of her symptoms and based on her treatment preferences, a two-stage surgical approach was planned. This involved an endoscopic transnasal transsphenoidal approach followed by a right craniotomy to achieve maximal tumor resection while minimizing potential complications. No residual disease or tumor remnants were present at the 6-month follow-up. The pituitary gland was preserved, and the patient's preoperative symptoms had fully resolved.
The preoperative diagnosis of concurrent skull base tumors is essential for effective management planning and determining the optimal surgical approach. The proximity of these tumors to critical neurovascular structures necessitates meticulous surgical planning to minimize adverse effects while ensuring maximal tumor resection. https://thejns.org/doi/10.3171/CASE24551.
鞍区和鞍旁区域同时出现拉克氏囊肿(RCCs)和脑膜瘤是一种极其罕见的临床情况。如先前报道所示,通过单一手术入路实现最大程度切除同时将不良事件降至最低具有挑战性,通常需要多种手术入路。
作者报告了一例49岁有肾移植史的女性病例,该患者因头痛就诊,分别被诊断为鞍区和蝶骨平台区域并存RCC和脑膜瘤。鉴于其症状持续时间长且难治,并基于其治疗偏好,计划采用两阶段手术方法。这包括先行内镜经鼻蝶窦入路,随后行右侧开颅手术,以实现最大程度的肿瘤切除,同时将潜在并发症降至最低。6个月随访时未见残留疾病或肿瘤残余。垂体得以保留,患者术前症状完全缓解。
术前诊断同时存在的颅底肿瘤对于有效的管理规划和确定最佳手术入路至关重要。这些肿瘤靠近关键神经血管结构,需要精心的手术规划,以在确保最大程度肿瘤切除的同时将不良影响降至最低。https://thejns.org/doi/10.3171/CASE24551