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择期腹腔镜胆囊切除术中的术中心肌梗死:一例报告

Intraoperative Myocardial Infarction During Elective Laparoscopic Cholecystectomy: A Case Report.

作者信息

Barghout Amr, Plummer Bethany

机构信息

Anaesthesia, Medway NHS Foundation Trust, Kent, GBR.

出版信息

Cureus. 2024 Dec 19;16(12):e76004. doi: 10.7759/cureus.76004. eCollection 2024 Dec.

Abstract

Laparoscopic cholecystectomy has become the gold standard for treating symptomatic cholelithiasis due to its minimally invasive nature and faster recovery times compared to traditional open surgery, but it is not without risks. A key component of this procedure is the creation of pneumoperitoneum. This is achieved by insufflating the abdomen with carbon dioxide (CO2). This process causes an increased intra-abdominal pressure (IAP), reduced venous return, and disrupted myocardial oxygen supply and demand. These changes may predispose vulnerable patients to acute cardiac events, particularly those with underlying cardiovascular risk factors. We present a case study of an intraoperative myocardial infarction (MI) that occurred during an elective laparoscopic cholecystectomy. During the procedure, the patient exhibited acute haemodynamic instability (bradycardia and hypotension). Electrocardiographic findings and cardiac biomarkers later confirmed the diagnosis. Immediate intraoperative interventions, including stabilisation of haemodynamics and removal of pneumoperitoneum. Postoperative recovery was monitored in the intensive care unit (ICU), with subsequent investigations identifying pre-existing but previously undiagnosed coronary artery disease as a contributing factor. This case highlights the importance of thorough preoperative cardiovascular evaluation, particularly in patients with risk factors for coronary artery disease, even for procedures considered minimally invasive. It also stresses the potential role of pneumoperitoneum in precipitating acute cardiac events due to its significant haemodynamic impact. Timely intraoperative management, combined with prompt access to cardiology expertise, evaluation, and invasive interventions, is essential for optimising patient outcomes in such cases.

摘要

与传统开放手术相比,腹腔镜胆囊切除术具有微创性且恢复时间更快,已成为治疗有症状胆结石的金标准,但它并非没有风险。该手术的一个关键环节是建立气腹。这是通过向腹腔内注入二氧化碳(CO₂)来实现的。这个过程会导致腹腔内压力(IAP)升高、静脉回流减少以及心肌氧供需失衡。这些变化可能使易患患者发生急性心脏事件,尤其是那些有潜在心血管危险因素的患者。我们报告一例择期腹腔镜胆囊切除术期间发生的术中心肌梗死(MI)病例。手术过程中,患者出现急性血流动力学不稳定(心动过缓和低血压)。心电图检查结果和心脏生物标志物后来证实了诊断。术中立即进行干预,包括稳定血流动力学和解除气腹。在重症监护病房(ICU)对术后恢复情况进行监测,随后的检查发现既往存在但之前未被诊断出的冠状动脉疾病是一个促成因素。该病例凸显了全面术前心血管评估的重要性,特别是对于有冠状动脉疾病危险因素的患者,即使是对于被认为是微创手术的手术。它还强调了气腹因其显著的血流动力学影响在引发急性心脏事件中的潜在作用。及时的术中管理,结合迅速获得心脏病学专家的专业知识、评估和有创干预,对于在此类病例中优化患者预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecab/11743408/db96a77ac454/cureus-0016-00000076004-i01.jpg

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